169260-95-1Relevant articles and documents
α- or β-Trifluoromethyl epoxysulfones: new C3 reagents for heterocyclisation
Laduron, Frederic,Janousek, Zdenek,Viehe, Heinz, G.
, p. 83 - 86 (1995)
The syntheses of α- and β-trifluoromethyl epoxysulfones 1 and 2 are described.Compound 1 reacts with nucleophiles and bis-nucleophiles to furnish trifluoromethyl ketones and trifluoromethyl heterocycles in good yield, while its isomer 2 leads to the opposite thiazole regioisomers with thioamides. - Keywords: Trifluoromethyl epoxysulfones; Heterocyclisation; Regioisomers; NMR spectroscopy; IR spectroscopy