55759-55-2

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 19493-09-5 Methylenetriphenylphosphorane 
• 3739-97-7 (trimethylsilyl)methylenetriphenylphosphorane 
• 407-25-0 trifluoroacetic anhydride 
• 603-35-0 triphenylphosphine 
• 169260-95-1 2-Trifluoromethyl-2-phenylsulfonyloxirane 
• 3739-98-8 triphenyl(trimethylsilylmethyl)phosphonium iodide 
• 653-27-0 α,α,α,2,3,4,5,6-octafluoroacetanilide 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Relevant academic research and scientific papers

The Wittig Reaction of some Fluorinated Amide Derivatives

Carboethoxymethylenetriphenylphosphorane 1 reacted with fluorinated amides 4,6,8 and 15 yielding products 12, 13, 14 and 3 respectively.

α- or β-Trifluoromethyl epoxysulfones: new C3 reagents for heterocyclisation

The syntheses of α- and β-trifluoromethyl epoxysulfones 1 and 2 are described.Compound 1 reacts with nucleophiles and bis-nucleophiles to furnish trifluoromethyl ketones and trifluoromethyl heterocycles in good yield, while its isomer 2 leads to the opposite thiazole regioisomers with thioamides. - Keywords: Trifluoromethyl epoxysulfones; Heterocyclisation; Regioisomers; NMR spectroscopy; IR spectroscopy

Synthesis and reactions of [1-(trialkylsilyl)alkylidene]triphenylphosphoranes

Alkylidenetriphenylphosphoranes 1 react with trialkyl halosilanes 2 to afford silylated alkylidenephosphoranes 5, which can be converted to acylated alkylidenephosphoranes 8 and 10 by trimethylsilyl carboxylates 6 or carboxylic anhydrides 10. Bis(acylalkylidenephosphoranes) 13-15 are available from 5 and bis(trimethylsilyl) dicarboxylates 12 or cyclic or polymeric anhydrides 16, 17.