16927-49-4 Usage
Description
4-ANILINO-3-NITROBENZOIC ACID, also known as ANB or NBP, is a chemical compound with the molecular formula C13H10N2O4. It is a nitroaromatic compound that appears as a yellow to orange crystalline powder. 4-ANILINO-3-NITROBENZOIC ACID is sparingly soluble in water but readily soluble in organic solvents. It is widely recognized for its applications in chemical analysis, titrations, and the synthesis of various organic compounds, including dyes and pharmaceuticals. Additionally, it plays a role in biochemical research as a pH indicator and in the development of fluorescent probes for enzyme activity studies.
Uses
Used in Chemical Analysis:
4-ANILINO-3-NITROBENZOIC ACID is used as a reagent in chemical analysis for its ability to provide accurate and reliable results in various analytical processes.
Used as an Indicator in Titrations:
In titrations, 4-ANILINO-3-NITROBENZOIC ACID serves as an indicator, helping to determine the endpoint of a titration process by signaling a color change.
Used in the Synthesis of Dyes:
4-ANILINO-3-NITROBENZOIC ACID is used as a key component in the synthesis of dyes, contributing to the development of a range of colorants for various applications.
Used in Pharmaceutical Synthesis:
4-ANILINO-3-NITROBENZOIC ACID is utilized in the synthesis of pharmaceuticals, playing a crucial role in the production of various medicinal agents.
Used in Biochemical Research as a pH Indicator:
4-ANILINO-3-NITROBENZOIC ACID is employed as a pH indicator in biochemical research, helping to measure and monitor pH levels in experimental settings.
Used in the Development of Fluorescent Probes for Enzyme Activity Studies:
In the field of enzyme activity studies, 4-ANILINO-3-NITROBENZOIC ACID is used in the development of fluorescent probes, enabling researchers to track and analyze enzyme activity with precision.
Check Digit Verification of cas no
The CAS Registry Mumber 16927-49-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,2 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16927-49:
(7*1)+(6*6)+(5*9)+(4*2)+(3*7)+(2*4)+(1*9)=134
134 % 10 = 4
So 16927-49-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H10N2O4/c16-13(17)9-6-7-11(12(8-9)15(18)19)14-10-4-2-1-3-5-10/h1-8,14H,(H,16,17)/p-1
16927-49-4Relevant articles and documents
Structural Modifications of Benzimidazoles via Multi-Step Synthesis and Their Impact on Sirtuin-Inhibitory Activity
Yoon, Yeong Keng,Choon, Tan Soo
, p. 1 - 8 (2016/01/29)
Benzimidazole derivatives have been shown to possess sirtuin-inhibitory activity. In the continuous search for potent sirtuin inhibitors, systematic changes on the terminal benzene ring were performed on previously identified benzimidazole-based sirtuin i
AGENT FOR TREATMENT OR PREVENTION OF DISEASES ASSOCIATED WITH ACTIVITY OF NEUROTROPHIC FACTORS
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Page/Page column 43, (2012/04/17)
A compound depicted by the formula below, or a pharmaceutically acceptable salt or solvate thereof. wherein, R1 represents (1) a C3-6 alkyl group,(2) a C1-6 alkyl group substituted with one or more substituent group(s) sel
3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b
Skinner, Philip J.,Cherrier, Martin C.,Webb, Peter J.,Sage, Carleton R.,Dang, Huong T.,Pride, Cameron C.,Chen, Ruoping,Tamura, Susan Y.,Richman, Jeremy G.,Connolly, Daniel T.,Semple, Graeme
, p. 6619 - 6622 (2008/04/02)
A series of 3-nitro-4-substituted-aminobenzoic acids were prepared and found to act as potent and highly selective agonists of the orphan human GPCR GPR109b, a low affinity receptor for niacin. No activity was observed at the closely homologous high affinity niacin receptor, GPR109a. A second series, comprising 6-amino-substituted nicotinic acids was, also prepared and several analogues showed comparable activity to the nitroaryl series.
