169514-86-7

Upstream product

• 100-53-8 phenylmethanethiol 
• 169736-18-9 (2S,3R,4S)-3,4-bis(benzyloxy)-2-[(benzyloxy)methyl]-5-methoxyoxolane 
• 144-55-8 sodium hydrogencarbonate 

Downstream Products

• 169736-19-0 benzyl 2,3,5-tri-O-benzyl-4-deoxy-4-thio-D-thioarabinofuranoside 

Relevant academic research and scientific papers

Synthesis and biological activity of certain 4'-thio-D- arabinofuranosylpurine nucleosides

A series of 4'-thio-D-arabinofuranosylpurine nucleosides was prepared and evaluated as potential anticancer agents. The details of a convenient and high-yielding synthesis of the carbohydrate precursor 1-O-acetyl-2,3,5-tri- O-benzyl-4-thio-D-arabinofurano

Preparation of thioarabinofuranosyl compounds and use thereof

Patients suffering from cancer are treated by being administered a compound represented by the following formula: wherein each R individually is H or an aliphatic or aromatic acyl group; A is selected from the group consisting of wherein X is selected from the group consisting of hydrogen, fluorine, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano and nitro. The above compounds also inhibit DNA replication in mammalian cells,

The synthesis and biological activity of certain 4'-thionucleosides

Results are presented on the synthesis and biological activity of several types of 4'-thionucleosides as potential anticancer agents. Detailed studies on the mechanism of action of 4'-thiothymidine are also presented.