126753-78-4Relevant academic research and scientific papers
Total synthesis of (±)-, (-)-, and (+)-oudemansin X
Umezawa,Nozawa,Nagumo,Akita
, p. 1111 - 1118 (2007/10/02)
Three kinds of oudemansin X, (-)-1, (+)-1 and (±)-1, were totally synthesized. The key point in the present chiral synthesis was the enantioselective acetylation of the racemic alcohols, (±)-5 and (±)-8, using lipase in an organic solvent. The synthetic (-)-1 was found to exhibit strong antifungal activity against several molds and yeasts.
Total synthesis of (-)-oudemansin X based on enzymatic resolution using immobilized lipase
Akita,Umezawa,Nozawa,Nagumo
, p. 757 - 760 (2007/10/02)
(-)-Oudemansin X (1) was synthesized based on enzymatic resolution of (±)-diol 5 using immobilized lipase.
Synthesis of Methyl 5-Aryl-3-oxo-4-pentenoates and Novel Substituted Cyclopentenones
Asokan, C. V.,Bhattacharji, S.,Ila, H.,Junjappa, H.
, p. 281 - 283 (2007/10/02)
The cinnamoyl- (1a-j) and (5-phenyl-2,4-pentadienoyl)- (1k) ketene dithioacetals are shown to undergo methanolysis in the presence of ether-boron trifluoride complex and mercury(II) chloride to the corresponding methyl 5-aryl-3-oxo-4-pentenoates 2a-j and 3-oxo-7-phenyl-4,6-heptadienoate (2k), respectively, in good yields.However, the corresponding (2-methylcinnamoyl)ketene dithioacetals 3a-f, under identical reaction conditions, undergo Nazarov cyclization to give the corresponding substituted cyclopentenones 4a-f.
