1701-25-3 Usage
Uses
Used in Pharmaceutical Industry:
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline is used as a building block for the synthesis of various organic compounds and pharmaceuticals. Its unique structure and functional groups contribute to the development of new drugs with improved therapeutic properties.
Used in Antimicrobial Applications:
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline is employed as an antimicrobial agent due to its ability to inhibit the growth of various microorganisms. Its halogenated quinoline structure is believed to interfere with essential cellular processes, leading to the disruption of microbial activity.
Used in Antimalarial Applications:
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline has been studied for its antimalarial properties, showing potential as a treatment for malaria. Its ability to target and inhibit the growth of Plasmodium parasites, which cause malaria, makes it a promising candidate for further research and development.
Used in Drug Discovery and Development:
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline serves as a valuable compound in drug discovery and development. Its unique chemical structure and potential biological activities make it a suitable candidate for the design and synthesis of new drugs targeting various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1701-25-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,0 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1701-25:
(6*1)+(5*7)+(4*0)+(3*1)+(2*2)+(1*5)=53
53 % 10 = 3
So 1701-25-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H7ClF3N/c1-6-3-2-4-7-8(12)5-9(11(13,14)15)16-10(6)7/h2-5H,1H3
1701-25-3Relevant academic research and scientific papers
Investigations into the flexibility of the 3D structure and rigid backbone of quinoline by fluorine addition to enhance its blue emission
Alapour,Zamisa,Silva,Alves,Omondi,Ramjugernath,Koorbanally
, p. 2316 - 2323 (2018/04/30)
Achieving the desired structures of organic molecules for targeted applications is vital. Folding caused by weak intermolecular forces plays an important part in their 3D structure. Powerful tools which enable us to do this are currently under investigation by researchers across the globe. On this account, quinoline was chosen as a model scaffold because of its rigid 3D structure. Addition of fluorine was found to result in increased flexibility of the structure with a decrease in the number of intermolecular interactions. This resulted in improvement of their photophysics and blue emission. A total of 19 novel fluoroquinoline molecules were synthesised in order to carry out this study. Of these, grown crystals of 10 compounds were successfully achieved and used. In addition, characterisation techniques such as NMR, HRMS, UV-vis and computational techniques were used to explore the 3D structure of these molecules.
PROLINE DERIVATIVES AND USE THEREOF AS DRUGS
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, (2008/06/13)
The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products. The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I) wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.
