17051-28-4

Basic information

• Product Name: 2-(1-methylethoxy)-1-phenylethanone
• Synonyms: 2-Isopropoxy-1-phenylethanone; ethanone, 2-(1-methylethoxy)-1-phenyl-
• CAS NO: 17051-28-4
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.2277
• Mol File: 17051-28-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 260.7°C at 760 mmHg
• Flash Point: 104.3°C
• Density: 1.005g/cm³
• Vapor Pressure: 0.012mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: 2-(1-methylethoxy)-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-methylethoxy)-1-phenylethanone(17051-28-4)
• EPA Substance Registry System: 2-(1-methylethoxy)-1-phenylethanone(17051-28-4)

Safety Data

• Hazardous Substances Data: 17051-28-4(Hazardous Substances Data)

Upstream product

• 13735-81-4 1-styrenyloxytrimethylsilane 
• 53578-07-7 isopropyl hypochlorite 
• 67-63-0 isopropyl alcohol 
• 98-88-4 benzoyl chloride 
• 84847-42-7 isopropoxy-acetonitrile 

Downstream Products

• 79598-14-4 2-Brom-2-isopropoxy-1,3-diphenyl-propan-1,3-dion 
• 79598-01-9 2-Isopropoxy-1,3-diphenyl-propan-1,3-dion 
• 79597-91-4 1-Hydroxy-2-isopropoxy-1,3-diphenyl-1-propen-2-on 
• 98-86-2 acetophenone 

Relevant articles and documents

Indium triflate: A mild and efficient Lewis acid catalyst for O-H insertion reactions of α-diazo ketones

Facile O-H insertion reactions of α-diazo ketones with aliphatic/aromatic alcohols or benzenethiol have been developed in the presence of indium triflate as a catalyst. These reactions provided good yields of α-alkoxy ketones. A comparative study with other Lewis acids establishes the reactivity of indium triflate in O-H insertion reactions of α-diazo ketones.

α-METHOXY KETONES BY THE REACTION OF TRIMETHYLSILYL ENOL ETHERS WITH LEAD TETRAACETATE IN METHANOL

Trimethylsilyl enol ethers of acetophenone, 2-acetylthiophene and 2-acetylfuran react with lead tetraacetate in methanol at room temperature to give the α-methoxy ketones in good yields.