17059-48-2

Basic information

• Product Name: 1H-INDENE,2,3-DIHYDRO-1,6-DIM
• Synonyms: 1H-INDENE,2,3-DIHYDRO-1,6-DIM;1,6-Dimethylindane
• CAS NO: 17059-48-2
• Molecular Formula: C11H14
• Molecular Weight: 146.23
• Mol File: 17059-48-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 213.5°Cat760mmHg
• Flash Point: 79.8°C
• Appearance: /
• Density: 0.944g/cm³
• Vapor Pressure: 0.239mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: 1H-INDENE,2,3-DIHYDRO-1,6-DIM(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDENE,2,3-DIHYDRO-1,6-DIM(17059-48-2)
• EPA Substance Registry System: 1H-INDENE,2,3-DIHYDRO-1,6-DIM(17059-48-2)

Safety Data

• Hazardous Substances Data: 17059-48-2(Hazardous Substances Data)

Usage

Structure

Dihydride derivative of indene, a polycyclic aromatic hydrocarbon

Appearance

Colorless to pale yellow liquid

Odor

Strong, sweet, floral

Uses

Building block in the synthesis of organic compounds (including pharmaceuticals, dyes, and fragrances), solvent, intermediate in chemical production

Hazards

Flammable, should be handled with care

InChI:InChI=1/C11H14/c1-8-3-5-10-6-4-9(2)11(10)7-8/h3,5,7,9H,4,6H2,1-2H3

Upstream product

• 10487-71-5 crotonyl chloride 
• 108-88-3 toluene 
• 52310-59-5 3,5-dimethyl-1H-indene 
• 58183-40-7 3-(p-tolyl)propionyl chloride 
• 1505-50-6 3-(4-Methylphenyl)propanoic acid 
• 24623-20-9 2,3-dihydro-6-methyl-1H-inden-1-one 
• 86119-84-8 phosphoric acid 
• 874532-47-5 3,5-dimethyl-2,3,4,5,6,7-hexahydro-inden-1-one 
• 145625-32-7 6-methyl-1-methylene-2,3-dihydro-1H-indene 

Relevant articles and documents

The design of dipeptide helical mimetics, Part I: The synthesis of 1,6-disubstituted indanes

The design and synthesis of conformationally restrained, non-peptide templates (1,6-disubstituted indanes) which allow the incorporation of two adjacent amino acid side-chains in an orientation similar to that found in alpha-helices is reported.

Steric Effects in the Synthesis of 1,7-Dialkylindans

Synthesis routes to 1-alkyl(CH3,C2H5,i-C3H7)-6-methylindans and 1-alkyl(CH3,C2H5,i-C3H7)-7-methylindans are described.Members of the latter series, especially 1-isopropyl-7-methylindan, are sterically hindered through a peri interaction.This effect manifests itself throughout the study and necessitated use of alternative synthesis routes.Yields in the Grignard, Peterson olefination, Reformatsky, and Wittig reactions as well as catalytic hydrogenation and Li/NH3 reduction of α,β-unsaturated acids were compared.