17105-65-6

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 121-45-9 phosphorous acid trimethyl ester 
• 123-11-5 4-methoxy-benzaldehyde 
• 105-13-5 4-Methoxybenzyl alcohol 
• 868-85-9 Dimethyl phosphite 
• 270921-39-6 (4-methoxyphenyl)methyl methyl carbonate 
• 2746-25-0 p-Methoxybenzyl bromide 

Downstream Products

• 205882-11-7 (E)-2-(4-methoxystyryl)furan 
• 299430-44-7 trans-3-(p-methoxystyryl)furan 
• 155827-34-2 (E)-3-(4-methoxystyryl)thiophene 
• 43212-67-5 1-(4-methoxyphenyl)-4-(4-methoxyphenyl)-1,3-butadiene 
• 22145-08-0 1-(4-methoxyphenyl)-4-phenyl-1,3-butadiene 
• 1694-19-5 E-1-(phenyl)-2-(4'-methoxyphenyl)ethene 
• 79958-53-5 (E)-1-(3,3-dimethylbut-1-en-1-yl)-4-methoxybenzene 
• 72078-54-7 4-methoxy-4'-methylstilbene 
• 2746-25-0 p-Methoxybenzyl bromide 
• 569-57-3 chlorotrianisene 
• 158751-26-9 [3-(2-(Tetrahydro-pyran-2-yloxy)-6-{2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-ethyl}-phenoxy)-benzyl]-phosphonic acid dimethyl ester 
• 246257-37-4 C₃₁H₃₅BrO₅ 
• 158751-24-7 3-{2-Methoxy-6-[2-(4-methoxy-phenyl)-ethyl]-phenoxy}-benzaldehyde 
• 158751-25-8 2-(3-Bromomethyl-phenoxy)-3-[2-(4-hydroxy-phenyl)-ethyl]-phenol 

Relevant academic research and scientific papers

Synthesis of α-Aryldiazophosphonates via a Diazo Transfer Reaction

The simple synthetic procedure for preparation of α-aryl-α-diazophosphonates via a diazo transfer reaction is proposed. Benzylphosphonates reacted with tosyl azide (TsN3) in the presence of potassium tert-butoxide (KOtBu) to afford diazophosphonates in a yield up to 79%. The proposed method is general. The reaction uses easily available starting materials, tolerates various functional groups, and may be applied for multi-gram scale synthesis.

Palladium-catalyzed benzylic substitution of benzyl carbonates with phosphorus nucleophiles

A wide range of benzyl carbonates reacted with dimethyl phosphonate or diphenylphosphine oxide in the presence of the palladium catalyst, [Pd(η3-allyl)Cl]2DPEphos, to give dimethyl benzylphosphonates and benzyldiphenylphosphine oxides in high yields. The catalytic phosphonylation was applied to the one-pot synthesis of alkenes from the benzyl esters.