171081-12-2Relevant academic research and scientific papers
Novel phosphitylating reagents containing a phosphorus-fluorine bond and their application in efficient synthesis of phosphorofluoridates and phosphorofluoridothionates
Dabkowski, Wojciech,Tworowska, Izabela
, p. 2462 - 2469 (2007/10/03)
Novel phosphitylating reagents containing a P-F bond are obtained in excellent yield from commercial materials. They react with alcohols at 20 °C in neutral solvents in the presence of tetrazole, chlorotrimethylsilane or benzoyl chloride to give the inter
Novel unique catalytic activating reagents in synthesis of biophosphates via the phosphoramidite route
Dabkowski, Wojciech,Tworowska, Izabela,Michalski, Jan,Cramer, Friedrich
, p. 1639 - 1644 (2007/10/03)
Trimethylchlorosilane (TMSCI) and 2,4-dinitrophenol are remarkably efficient activators in reaction of P(III) amides with nucleosides to give P(III) esters in excellent yield.
Trimethylchlorosilane: A novel activating reagent in nucleotide synthesis via the phosphoramidite route
Dabkowski, Wojciech,Tworowska, Izabela,Michalski, Jan,Cramer, Friedrich
, p. 877 - 878 (2007/10/03)
Trimethylchlorosilane (TMSCl) is a remarkably efficient activator in the reaction of phosphorus(III) amides with nucleosides to give phosphorus(III) esters in excellent yield.
First Synthesis of Nucleosidyl Phosphorofluoridothioates and a Convenient Synthesis of Nucleosidyl Phosphorofluoridates
Dabkowski, Wojciech,Tworowska, Izabela
, p. 727 - 728 (2007/10/03)
The first synthesis of 3'- or 5'-nucleosidyl phosphorofluoridothioates RO-P(S)(OH)F have been accomplished via nucleosidyl phosphoramidofluoridates RO-P(NPr12)F.An analogous convenient procedure has been employed to prepare 3'- or 5'-nucleosidy
