171081-12-2

Basic information

• Product Name: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridite
• Synonyms: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridite
• CAS NO: 171081-12-2
• Molecular Weight: 663.639
• Mol File: 171081-12-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridite(CAS DataBase Reference)
• NIST Chemistry Reference: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridite(171081-12-2)
• EPA Substance Registry System: O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridite(171081-12-2)

Safety Data

• Hazardous Substances Data: 171081-12-2(Hazardous Substances Data)

Upstream product

• 109-78-4 3-Hydroxypropionitrile 
• 162611-40-7 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl-(N,N-diisopropylamino)phosphorofluoridite 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 191151-90-3 O-(2-cyanoethyl) N,N-diisopropylfluorophosphoramidite 

Downstream Products

• 57538-75-7 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen phosphorofluoridate 
• 182370-37-2 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] hydrogen thiophosphorofluoridate 
• 171081-20-2 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) thiophosphorofluoridate 
• 171081-16-6 O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] O-(2-cyanoethyl) phosphorofluoridate 

Relevant articles and documents

Novel phosphitylating reagents containing a phosphorus-fluorine bond and their application in efficient synthesis of phosphorofluoridates and phosphorofluoridothionates

Novel phosphitylating reagents containing a P-F bond are obtained in excellent yield from commercial materials. They react with alcohols at 20 °C in neutral solvents in the presence of tetrazole, chlorotrimethylsilane or benzoyl chloride to give the inter

Trimethylchlorosilane: A novel activating reagent in nucleotide synthesis via the phosphoramidite route

Trimethylchlorosilane (TMSCl) is a remarkably efficient activator in the reaction of phosphorus(III) amides with nucleosides to give phosphorus(III) esters in excellent yield.