171499-89-1Relevant academic research and scientific papers
Synthesis and glycosidase inhibitory activity of noeurostegine - A new and potent inhibitor of β-glucoside hydrolases
Rasmussen, Tina Secher,Jensen, Henrik Helligso
supporting information; experimental part, p. 433 - 441 (2010/02/16)
A new, stable hemi-aminal nor-tropane christened noeurostegine was synthesised in 22 steps from levoglucosan and tested for inhibitory activity against glycoside hydrolases. Sweet almond and Thermotoga maritimaβ- glucosidases, coffee bean α-galactosidase,
Design and synthesis of 2-acetamidomethyl derivatives of isofagomine as potential inhibitors of human lysosomal β-hexosaminidases
Van Den Berg, Richard J. B. H. N.,Donker-Koopman, Wilma,Van Boom, Jacques H.,Aerts, Hans M. F. G.,Noort, Daan
, p. 891 - 902 (2007/10/03)
As part of a program towards the development of specific inhibitors of human lysosomal β-hexosaminidase for use as chemical chaperones in therapy of GM2 gangliosidosis related diseases, the synthesis of 2-acetamidomethyl derivatives of isofagom
Synthesis of the first pseudosugar-C-disaccharide. A potential antigen for eliciting glycoside-bond forming antibodies with catalytic groups
Barbaud,Barbaud, Christel,Bols,Bols, Mikael,Lundt,Lundt, Inge,Sierks,Sierks, Michael R.
, p. 9063 - 9078 (2007/10/02)
A number of synthetic routes to the first pseudo-C-disaccharide ever prepared has been studied. The compound, methyl-7-((1S,3R,4R,5S,6S)-1-amino-3-hydroxymethyl-4,5,6-trihydroxycyc lohexyl)-6,7-dideoxy-α-D-gluco-heptopyranoside (I), is structurally relate
