17158-87-1

Basic information

• Product Name: 1-(chloro-(2-Methylpropoxy)phosphoryl)oxy-2-Methyl-propane
• Synonyms: 1-(chloro-(2-Methylpropoxy)phosphoryl)oxy-2-Methyl-propane
• CAS NO: 17158-87-1
• Molecular Formula: C₈H₁₈ClO₃P
• Molecular Weight: 260.652281
• Mol File: 17158-87-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 267.9°Cat760mmHg
• Flash Point: 132.5°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 0.0131mmHg at 25°C
• Refractive Index: 1.43
• CAS DataBase Reference: 1-(chloro-(2-Methylpropoxy)phosphoryl)oxy-2-Methyl-propane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(chloro-(2-Methylpropoxy)phosphoryl)oxy-2-Methyl-propane(17158-87-1)
• EPA Substance Registry System: 1-(chloro-(2-Methylpropoxy)phosphoryl)oxy-2-Methyl-propane(17158-87-1)

Safety Data

• Hazardous Substances Data: 17158-87-1(Hazardous Substances Data)

Usage

General Description

1-(chloro-(2-methylpropoxy)phosphoryl)oxy-2-methyl-propane, also known as methylpropylphosphonic acid dichloride, is a chemical compound that consists of a phosphorus atom bonded to a chlorine atom and two methyl groups, as well as an oxygen atom bonded to a phosphoryl group and a propoxy group. It is commonly used as a precursor for the synthesis of organophosphorus compounds, which have various industrial and agricultural applications. 1-(chloro-(2-methylpropoxy)phosphoryl)oxy-2-methyl-propane is highly reactive and can undergo substitution reactions with nucleophiles, making it a valuable building block for the production of more complex organic molecules. It is also important to note that this compound should be handled with caution due to its potential hazards and toxic properties.

InChI:InChI=1/C8H18ClO3P/c1-7(2)5-11-13(9,10)12-6-8(3)4/h7-8H,5-6H2,1-4H3

Upstream product

• 13529-77-6 phosphonic acid diisobutyl ester 
• 78-83-1 2-methyl-propan-1-ol 
• 1189-24-8 diisobutyl phosphite 
• 75-44-5 phosgene 
• 1606-96-8 triisobutyl phosphite 

Downstream Products

• 7284-47-1 phosphoric acid diisobutyl ester-(4-nitro-phenyl ester) 
• 6303-30-6 diisobutyl phosphoric acid 
• 563-22-4 phosphorofluoridic acid diisobutyl ester 
• 814-26-6 Phosphorsaeure-diisobutylester-(2-methacryloyloxy-ethylester) 
• 126-71-6 triisobutyl phosphate 
• 1261067-39-3 17-β-O-{1-[2-carboxy-(2-hydroxy-4-methoxy-3-carboxamido)anilido]ethyl}1,3,5-estratriene-3-diisobutyl phosphate 
• 106841-87-6 phenyl-amidophosphoric acid diisobutyl ester 

Relevant articles and documents

N,N-Dichloro poly(styrene-co-divinyl benzene) sulfonamide polymeric beads: an efficient and recyclable reagent for the synthesis of dialkyl chlorophosphates from dialkylphosphites at room temperature

An efficient and operationally simple method is developed for the synthesis of dialkyl chlorophosphates from dialkylphosphites using a new chlorine bearing reagent, N,N-dichloro poly(styrene-co-divinyl benzene) sulfonamide in the form of polymeric beads. The reagent afforded dialkyl chlorophosphates at room temperature, and is recyclable.

N-tert-butyl-N-chlorocyanamide: A mild and efficient chlorinating agent for the synthesis of dialkyl/diaryl chlorophosphates

An efficient reagent for the synthesis of dialkyl/diaryl chlorophosphates has been developed. N-tert-Butyl-N-chlorocyanamide acts as a chlorinating agent both in polar as well in non-polar medium and the transformation of dialkyl/diaryl phosphites to the dialkyl/diaryl chlorophosphates takes place rapidly under mild conditions in quantitative yields. Copyright

Reactivity of an electrophilic hypervalent iodine trifluoromethylation reagent with hydrogen phosphates - A mechanistic study

The electrophilic trifluoromethylation of hydrogen phosphates with the reagent trifluoromethyl-1,3-dihydro-3,3-dimethyl-1,2-benziodoxole (1) was studied by means of initial rates determined for pseudo first order setups and subsequent Taft analysis of the calculated relative rates. A positive polar sensitivity factor, indicative of a negative charge forming during the rate-determining step, was found for the whole data set.