1717-22-2

Basic information

• Product Name: 5-Fluorobiphenyl-2-amine
• Synonyms: 5-Fluorobiphenyl-2-amine;4-Fluoro-2-phenylaniline;5-Fluoro[1,1'-biphenyl]-2-amine
• CAS NO: 1717-22-2
• Molecular Formula: C₁₂H₁₀FN
• Molecular Weight: 187.21
• Mol File: 1717-22-2.mol
• Article Data: 49

Chemical Properties

• Boiling Point: 311.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.161±0.06 g/cm3(Predicted)
• PKA: 3.87±0.10(Predicted)
• CAS DataBase Reference: 5-Fluorobiphenyl-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Fluorobiphenyl-2-amine(1717-22-2)
• EPA Substance Registry System: 5-Fluorobiphenyl-2-amine(1717-22-2)

Safety Data

• Hazardous Substances Data: 1717-22-2(Hazardous Substances Data)

Upstream product

• 61272-76-2 4-fluoro-2-iodoaniline 
• 98-80-6 phenylboronic acid 
• 255724-71-1 5-fluoro-2-iodoaniline 
• 108-86-1 bromobenzene 
• 100-63-0 phenylhydrazine 
• 371-40-4 4-fluoroaniline 
• 59-88-1 phenylhydrazine hydrochloride 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 1003-98-1 2-bromo-4-fluoroaniline 
• 700-36-7 2-bromo-4-fluoronitrobenzene 
• 1073-06-9 3-fluorobromobenzene 
• 591-50-4 iodobenzene 
• 1478-01-9 5-fluoro-2-nitro-1,1’-biphenyl 

Downstream Products

• 343-40-8 3-fluoro-9H-fluorene 
• 1283747-35-2 3-fluoro-9-(phenylsulfonyl)-9H-carbazole 
• 1428265-16-0 2-fluoro-6-phenylphenanthridine 
• 1360593-30-1 C₁₉H₁₆FNO₂S 
• 391-45-7 3-fluoro-9H-carbazole 

Relevant articles and documents

CoPc-catalyzed selective radical arylation of anilines with arylhydrazines for synthesis of 2-aminobiaryls

CoPc-catalyzed selective radical arylation of anilines with arylhydrazines to afford 2-aminobiaryls in moderate to good yields is described. This journal is the Partner Organisations 2014.

α-Bromoacrylic Acids as C1 Insertion Units for Palladium-Catalyzed Decarboxylative Synthesis of Diverse Dibenzofulvenes

Herein α-bromoacrylic acids have been employed as C1 insertion units to achieve the palladium-catalyzed [4 + 1] annulation of 2-iodobiphenyls, which provides an efficient platform for the construction of diverse dibenzofulvenes. This protocol enables the formation of double C(aryl)-C(vinyl) bonds via a C(vinyl)-Br bond cleavage and decarboxylation. It is particularly noteworthy that the method features a broad substrate scope, and various interesting frameworks, such as bridged ring, fused (hetero)aromatic ring, and divinylbenzene, can be successfully incorporated into the products.

Asymmetric palladium complex, preparation method and application thereof in catalysis of olefin polymerization

The invention belongs to the technical field of chemical synthesis, and particularly relates to an asymmetric palladium complex, a preparation method and application thereof in catalysis of olefin polymerization. According to the asymmetric alpha-diimine palladium complex disclosed by the invention, a rigid camphanyl skeleton with large steric hindrance is adopted, so that the axial steric hindrance effect of a catalyst can be improved, and the thermal stability and polymerization activity of the catalyst are further improved; aniline with only one phenyl substituted ortho-position is adopted, and the other ortho-position (6-position) has no substituent, so that the coordination of olefin substituted by large steric hindrance is facilitated, and the catalytic activity is improved; in addition, the complex is simple to synthesize and high in yield, has wide adaptability to polymerization of large-steric-hindrance substituted olefin, and has high economic value.

Scalable electrochemical synthesis of diaryliodonium salts

Cyclic and acyclic diaryliodonium are synthesised by anodic oxidation of iodobiaryls and iodoarene/arene mixtures, respectively, in a simple undivided electrolysis cell in MeCN-HFIP-TfOH without any added electrolyte salts. This atom efficient process does not require chemical oxidants and generates no chemical waste. More than 30 cyclic and acyclic diaryliodonium salts with different substitution patterns were prepared in very good to excellent yields. The reaction was scaled-up to 10 mmol scale giving more than four grams of dibenzo[b,d]iodol-5-ium trifluoromethanesulfonate (>95%) in less than three hours. The solvent mixture of the large-scale experiment was recovered (>97%) and recycled several times without significant reduction in yield.