17183-98-1

Basic information

• Product Name: (1alpha)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)pregna-4,6-diene-3,20-dione
• Synonyms: 6-Chloro-1alpha-(chloromethyl)-17-hydroxypregna-4,6-diene-3,20-dione acetate;Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-chloro-1-(chloromethyl)-, (1a)-;6-chioro-1α-chloromethyl-3,20-dioxo-pregna-4,6-dien-17α-acetoxy;1-CHLOROMETHYL-6-CHLORO-6-DEHYDRO-17ACETOXY PROGESTRONE;(1S,8R,9S,10S,13S,14S,17R)-17-acetyl-6-chloro-1-(chloroMethyl)-10,13-diMethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate;(1alpha)-17-(Acetyloxy)-6-chloro-1-(chloroMethyl)prehna-4,6-diene-3,20-dione;Color Pronk chloride;1-ChlormehylL-6-Chloro-6-Dehydro- 17α-Acetoxy-Progesterone
• CAS NO: 17183-98-1
• Molecular Formula: C₂₄H₃₀Cl₂O₄
• Molecular Weight: 453.4
• EINECS: 1308068-626-2
• Product Categories: Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
• Mol File: 17183-98-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 554.4 °C at 760 mmHg
• Flash Point: 181.7 °C
• Appearance: /
• Density: 1.27
• Vapor Pressure: 0-0Pa at 20-30℃
• Refractive Index: 1.564
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
• CAS DataBase Reference: (1alpha)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)pregna-4,6-diene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (1alpha)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)pregna-4,6-diene-3,20-dione(17183-98-1)
• EPA Substance Registry System: (1alpha)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)pregna-4,6-diene-3,20-dione(17183-98-1)

Safety Data

• Hazardous Substances Data: 17183-98-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 17183-98-1 differently. You can refer to the following data:
1. An impurity of Cyproterone acetate (C989100)
2. 1α-(Chloromethyl) Chlormadinone Acetate (Cyproterone Acetate EP Impurity C) is an impurity of Cyproterone acetate (C989100), as antiandrogenic steroid.

InChI:InChI=1/C24H30Cl2O4/c1-13(27)24(30-14(2)28)8-6-18-17-11-21(26)20-10-16(29)9-15(12-25)23(20,4)19(17)5-7-22(18,24)3/h10-11,15,17-19H,5-9,12H2,1-4H3/t15-,17+,18+,19+,22+,23-,24+/m1/s1

Upstream product

• 2701-50-0 1,2α-methylene-Δ4,6-pregnadiene-17α-ol-3,20-dione-17-acetate 
• 2098-65-9 17α-hydroxy-1α,2α-methylene-4,6-pregnadiene-3,20-dione 
• 66212-25-7 1,4,6-triene-3,20-dione-17α-hydroxyprogesterone 
• 15423-97-9 1,2α-methylene-6,7α-oxido-Δ4-pregnen-17α-ol-3,20-dione-17-acetate 

Downstream Products

• 427-51-0 cyproterone acetate 

Relevant articles and documents

Preparation process of cyproterone acetate (by machine translation)

The invention relates to a preparation process of cyproterone acetate, which comprises the following steps: ketal reaction; cyclopropanecarboxylic hydrolysis reaction; acetyl reaction; epoxy reaction; chlorinated reaction; a cyclization reaction; the invention can overcome the original process product is difficult to solve in the benzene remains the problem of, and the start is simple in raw material, reaction is stable, the total yield is high. (by machine translation)