171876-69-0

Upstream product

• 30992-63-3 5-benzyloxy-2-hydroxyacetophenone 
• 67-64-1 acetone 
• 31366-85-5 6-hydroxy-2,2-dimethyl-chroman-4-one 
• 100-39-0 benzyl bromide 
• 96-22-0 pentan-3-one 
• 123-75-1 pyrrolidine 
• 490-78-8 2,5-Dihydroxyacetophenone 

Downstream Products

• 223749-51-7 6-benzyloxy-2,2-dimethylchroman-4-ol 
• 223749-66-4 (3R,4R)-6-benzyloxy-2,2-dimethyl-3,4-epoxychroman 
• 118701-77-2 6-benzyloxy-2,2-dimethyl-2H-chromen 

Relevant academic research and scientific papers

Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and pharmaceutical preparations comprising them

Compounds of the formula I having the meanings of the substituents indicated in the claims are outstandingly efficacious substances for producing medicaments for the prophylaxis and for the therapy of cardiovascular disorders, in particular arrhythmias, f

Synthesis and activity of novel and selective Iks-channel blockers

Since the discovery of the IKs-potassium channel as the slowly activating component of the delayed rectifier current (Ik) in cardiac tissue, the search for blockers of this current has been intense. During the screening of KATP

Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and pharmaceutical preparations comprising them

Compounds of the formula I STR1 having the meanings of the substituents indicated in the claims are outstandingly efficacious substances for producing medicaments for the prophylaxis and for the therapy of cardiovascular disorders, in particular arrhythmias, for the treatment of ulcers of the gastrointestinal region or for the treatment of diarrheal disorders.

Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them

Sulfonamide-substituted benzopyran derivatives, processes for their preparation, their use as a medicament, and pharmaceutical preparations comprising them Compounds of the formula I STR1 having the meanings of the substituents indicated in the claims are

SULFONAMIDE DERIVATIVES OF BENZENEFUSED HYDROXY SUBSTITUTED CYCLOALKYL AND HETEROCYCLIC RING COMPOUNDS

Compounds of the formula STR1 and pharmaceutically acceptable salts and prodrugs thereof, wherein X 1, Ar, X, Y 1, R. sup.1, R. sup.2, R 3, R 5 and n are defined below, which are inhibitors of the production of leukotrienes and/or blockers of leukotriene

Aldol Condensation of 6-Alkoxy-2,2-dimethylchroman-4-ones with Substituted Benzaldehydes Using Tetramethylorthosilicate and Potassium Fluoride

The aldol condensation of 6-alkoxy-2,2-dimethylchromanones 1 or 2 with substituted benzaldehydes in the presence of tetramethylorthosilicate and potassium fluoride affords 6-alkoxy-3-benzylidene-2,2-dimethylchromanones 5-10 while other conventional methods were unsuccessful.