172227-59-7 Usage
Uses
Used in Biomedical Research:
6-(4-ACETAMIDO-1 8-NAPHTHALAMIDO) HEXANO is used as a fluorescent label for in situ hybridization (ISH) with labeled complementary synthetic oligonucleotides (ODNs). This application allows researchers to detect and visualize specific nucleic acid sequences within cells or tissue samples, providing valuable insights into gene expression patterns and the localization of specific genetic material.
Used in Diagnostic Applications:
In the field of diagnostics, 6-(4-ACETAMIDO-1 8-NAPHTHALAMIDO) HEXANO is used as a fluorescent marker for the detection and identification of various pathogens, such as bacteria and viruses. Its strong fluorescence properties enable the rapid and accurate identification of these microorganisms, aiding in the diagnosis and treatment of infectious diseases.
Used in Drug Development:
6-(4-ACETAMIDO-1 8-NAPHTHALAMIDO) HEXANO can also be employed in the development of new drugs, particularly those targeting specific genetic or molecular pathways. Its ability to bind with specific biological molecules makes it a useful tool for the design and synthesis of targeted therapeutic agents.
Used in Analytical Chemistry:
In analytical chemistry, 6-(4-ACETAMIDO-1 8-NAPHTHALAMIDO) HEXANO is used as a fluorescent probe for the detection and quantification of various analytes, such as metal ions, small molecules, and biomolecules. Its strong fluorescence signal allows for sensitive and accurate measurements, making it a valuable tool in a wide range of analytical applications.
Used in Environmental Monitoring:
6-(4-ACETAMIDO-1 8-NAPHTHALAMIDO) HEXANO can be utilized in environmental monitoring to detect and quantify pollutants or contaminants in water, soil, and air samples. Its fluorescence properties enable the sensitive detection of these substances, helping to assess environmental quality and inform remediation efforts.
Used in Forensic Science:
In forensic science, 6-(4-ACETAMIDO-1 8-NAPHTHALAMIDO) HEXANO can be employed as a fluorescent marker for the detection and analysis of trace evidence, such as DNA, fingerprints, or other biological materials. Its ability to bind with specific molecules and produce a strong fluorescence signal makes it a valuable tool for forensic investigators.
Check Digit Verification of cas no
The CAS Registry Mumber 172227-59-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,2,2,2 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 172227-59:
(8*1)+(7*7)+(6*2)+(5*2)+(4*2)+(3*7)+(2*5)+(1*9)=127
127 % 10 = 7
So 172227-59-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H20N2O5/c1-12(23)21-16-10-9-15-18-13(16)6-5-7-14(18)19(26)22(20(15)27)11-4-2-3-8-17(24)25/h5-7,9-10H,2-4,8,11H2,1H3,(H,21,23)(H,24,25)
172227-59-7Relevant academic research and scientific papers
Singh, Nidhi,Srivastava, Ritika,Singh, Anuradha,Singh, Ramendra K.
, p. 1431 - 1438 (2016)
Derivatives of 4-amino-1,8-naphthalimide containing a free alkyl chain bearing carboxyl group as linker and different substituents at 4-amino function have been synthesized, characterized and studied for their photophysical properties. Steady state fluorescence studies showed quantum yield varied from 0.45 to 0.65 with Stokes shift in the range of 5824–8558?cm?1. Spectroscopic and physicochemical parameters, like electronic absorption, emission, and extinction coefficient were investigated in order to explore the analytical potential of compounds. Solvatochromic studies demonstrated that all compounds were sensitive towards the polarity of different solvents showing the highest degree of fluorescence in acetonitrile. In addition, the compounds in the presence of ions, viz. Na+, K+ and Mg2+ at concentration of 0.1–2 equivalents, showed a decreasing trend in fluorescence with increasing ionic concentration. TCSPC set – up was used to measure the fluorescence lifetime of compounds, which was found to be bi-exponential with longer and shorter component at their respective amplitudes. The average lifetime of compounds was observed to be 5.76–9.96?ns indicating the possibility of their greater utilization in research and diagnosis.
Chang, Young-Tae,Schultz, Peter G.
, p. 2479 - 2482 (1999)
A versatile fluorescence labeling method employing support bound nitrophenyl, N-hydroxysuccinimidyl, 1-hydroxybenzotriazoyl and oxime active esters is described. The relative kinetic properties of different esters were systematically compared using an env
A novel bifunctional fluorescent tag for use in molecular biology
Dubey, Krishna K.,Singh, Ramendra K.,Misra, Krishna
, p. 876 - 878 (2007/10/03)
Synthesis and characterization of a new, highly fluorescent label, 4-acetylamino-1,8-naphthalimide-N-caproic acid (6) have been described.The synthesis of this molecule has been effected starting from acenaphthene, a non-fluorescent starting compound, through a series of chemical reactions.
