17223-18-6

Basic information

• Product Name: N,N'-(1,3-Phenylene)bisbenzamide
• Synonyms: N,N'-(1,3-Phenylene)bisbenzamide;N-[3-(benzoylamino)phenyl]benzamide
• CAS NO: 17223-18-6
• Molecular Formula: C₂₀H₁₆N₂O₂
• Molecular Weight: 316.35
• Mol File: 17223-18-6.mol
• Article Data: 12

Chemical Properties

• Melting Point: 240 °C(Solv: ethanol (64-17-5))
• Boiling Point: 361.5±25.0 °C(Predicted)
• Appearance: /
• Density: 1.279±0.06 g/cm3(Predicted)
• PKA: 12.79±0.70(Predicted)
• CAS DataBase Reference: N,N'-(1,3-Phenylene)bisbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-(1,3-Phenylene)bisbenzamide(17223-18-6)
• EPA Substance Registry System: N,N'-(1,3-Phenylene)bisbenzamide(17223-18-6)

Safety Data

• Hazardous Substances Data: 17223-18-6(Hazardous Substances Data)

Upstream product

• 541-69-5 m-phenylenediamine dihydrochloride 
• 98-88-4 benzoyl chloride 
• 615-28-1 o-phenylenediamine dihydrochloride 
• 4771-08-8 N-(3-nitrophenyl)benzamide 
• 99-09-2 3-nitro-aniline 
• 99-65-0 meta-dinitrobenzene 
• 108-45-2 m-phenylenediamine 
• 65-85-0 benzoic acid 

Downstream Products

• 13387-13-8 2,6-diphenyl-benzo[1,2-d;5,4-d']bisthiazole 
• 1237478-04-4 C₂₈H₃₄N₂O₆P₂ 
• 1237478-05-5 C₃₂H₄₅N₂O₉P₃ 
• 1237478-07-7 C₃₆H₅₆N₂O₁₂P₄ 
• 19250-69-2 N-(2-phenyl-1⁽³⁾H-benzoimidazol-5-yl)-benzamide 
• 197570-88-0 N,N'-(4-nitro-m-phenylene)-bis-benzamide 

Relevant articles and documents

Synthesis of poly(m-phenyleneisophthalamide) by solid-state polycondensation of isophthalic acid with m-phenylenediamine

The synthesis of poly(m-phenyleneisophthalamide) was performed by thermal solid-phase polymerization from isophthalic acid and m-phenylenediamine without using any solvents or condensation agents. The two-stage heating process was conducted. The oligo(m-p

Synthesis of New Bulky Bis(amidine) with the Conformationally Rigid meta-Phenylene Bridge and Its Dilithium Derivative [1,3-C6H4{NC(Ph)N(2,6-iso-Pr2C6H3)}2]Li2(TMEDA)2

Abstract: The reaction of 2,6-diisopropylaniline with m-phenylenedibenzimidoyl chloride 1,3-C6H4{N=C(Ph)Cl}2 in the presence of triethylamine in a toluene solution affords bis(amidine) 1,3-C6H4{NC(Ph)

Synthesis of 2-Amino-1,3-dienes from Propargyl Carbonates via Palladium-Catalyzed Carbon-Nitrogen Bond Formation

A catalytic method to synthesize 1,3,-dienes from propargylic precursors is reported. This palladium-catalyzed carbon-nitrogen bond-forming reaction furnishes 2-amino-1,3-dienes in excellent yields (up to 98%) and shows a broad tolerance to functional group diversity. The reaction has been demonstrated for over 30 amine substrates, including anilines and indoles, and proceeds under mild neutral conditions. The resulting 1,3-dienes are of great synthetic interest because of their further reaction potential.

Design, synthesis and structure-activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton

Human sirtuin 2 (SIRT2) is an attractive target molecule for development of drugs to treat neurodegenerative diseases and cancer, because SIRT2 inhibitors have a protective effect against neurodegeneration and an anti-proliferative effect on cancer stem c