172271-62-4Relevant articles and documents
Synthesis and characterization of new photolabile phorbol esters for affinity labeling of protein kinase C
Irie,Ishii,Ohigashi,Wender,Miller,Takeda
, p. 2164 - 2173 (1996)
Three new photolabile phorbol esters (3, 6, and 9) with a diazoacetyl group at positions 3, 12, and 13, respectively, have been synthesized from phorbol (1a) and found to bind with significant affinity to the peptide (peptide C) incorporating the phorbol
Photoaffinity labeling of PKC isozymes by phorbol ester derivatives
Uotsu, Koichiro,Sodeoka, Mikiko,Shibasaki, Masakatsu
, p. 1117 - 1126 (2007/10/03)
Photoaffinity probes PPDA and PPTD, which have diazoacetyl and trifluorodiazopropionyl group at C-13 position in phorbol, respectively, were synthesized. Photoaffinity labeling of protein kinase C isozymes by both the probes resulted in specific cross-linking. Copyright (C) 1998 Elsevier Science Ltd.