17283-12-4

Basic information

• Product Name: 3-4-dimethylpropiophenone
• Synonyms: 3-4-dimethylpropiophenone;1-(3,4-dimethylphenyl)propan-1-one(SALTDATA: FREE);Propiophenone, 3^,4^-dimethyl-
• CAS NO: 17283-12-4
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.231
• Mol File: 17283-12-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 260.6°C at 760 mmHg
• Flash Point: 105°C
• Appearance: /
• Density: 0.954g/cm³
• Vapor Pressure: 0.0121mmHg at 25°C
• Refractive Index: 1.506
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-4-dimethylpropiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-4-dimethylpropiophenone(17283-12-4)
• EPA Substance Registry System: 3-4-dimethylpropiophenone(17283-12-4)

Safety Data

• Hazardous Substances Data: 17283-12-4(Hazardous Substances Data)

Usage

General Description

3-4-dimethylpropiophenone, also known as 1-(3,4-dimethylphenyl)propan-1-one, is an organic compound that belongs to the family of ketones. It is a colorless liquid with a strong, sweet odor and is used as a precursor in the production of various pharmaceuticals, fragrances, and flavorings. Its chemical structure consists of a propanone group attached to a benzene ring with two methyl groups positioned at the 3 and 4 positions on the benzene ring. 3-4-dimethylpropiophenone is an important intermediate in organic synthesis and is utilized in the manufacturing of a variety of commercial products. It is also a commonly used chemical in research and laboratory settings for its versatility in creating different compounds.

InChI:InChI=1/C11H14O/c1-4-11(12)10-6-5-8(2)9(3)7-10/h5-7H,4H2,1-3H3

Upstream product

• 5973-71-7 3,4-dimethylbenzaldehyde 
• 95-47-6 o-xylene 
• 79-03-8 propionyl chloride 
• 104174-13-2 3,4-Xylyl-aethylcarbinol 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 1226000-97-0 C₁₃H₁₆O₃ 
• 1202873-64-0 C₁₃H₁₆N₂O 
• 1097726-59-4 C₂₄H₂₈N₄O₃ 
• 1097726-51-6 C₂₄H₂₇N₃O₄ 
• 806601-27-4 (3,4-Dimethyl-phenyl)-(1-dimethylamino-ethyl)-keton 
• 847448-11-7 {[1-(3,4-dimethyl-phenyl)-propyl]-formyl-amino}-acetic acid methyl ester 
• 473732-70-6 1-(3,4-dimethylphenyl)propan-1-amine 

Relevant articles and documents

Palladium-promoted asymmetric cycloaddition reaction of arsole via an unusual exo-endo stereochemically controlled method

Asymmetric cycloaddition reaction between 3,4-dimethyl-1-phenylarsole and ethyl vinyl ketone was promoted by the palladium complex containing ortho-metalated (S)-[1-(dimethylamino)ethyl]naphthalene as the chiral auxiliary. The keto group in the resulting arsanorbornene cycloadducts could be located stereospecifically in the endo or exo position by controlling the electronic properties of the organopalladium promoter. In the intermolecular cycloaddition reaction, a pair of separable diastereomeric palladium complexes was obtained in the ratio of 2:1. In the intramolecular process, however, only one As-O bidentate arsanorbornene palladium complex was produced stereoselectively. The arsenic-elimination reaction was readily observed on the corresponding endo- and exo-ketoarsine ligands. The absolute configuration and the coordination property of the enantiomerically pure endo-cycloadduct had been established by single-crystal X-ray analysis.

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Compounds of formula I wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.