1729-03-9Relevant academic research and scientific papers
Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists
Matos, Maria Jo?o,Vilar, Santiago,Vazquez-Rodriguez, Saleta,Kachler, Sonja,Klotz, Karl-Norbert,Buccioni, Michela,Delogu, Giovanna,Santana, Lourdes,Uriarte, Eugenio,Borges, Fernanda
, p. 2577 - 2587 (2019/12/25)
Adenosine receptors participate in many physiological functions. Molecules that may selectively interact with one of the receptors are favorable multifunctional chemical entities to treat or decelerate the evolution of different diseases. 3-Arylcoumarins
Hydrolysis and substitution effects on the optical properties of coumarin derivatives studied by vibrational spectroscopy and DFT calculation
Khemakhem, Sirine,Elleuch, Slim,Ben Azaza, Najla,Ammar, Houcine,Abid, Younes
, p. 65 - 72 (2018/05/28)
A series of coumarin derivatives have been successfully synthesized. All compounds have been characterized by means of IR and Raman vibrational spectroscopic techniques at the solid state level. Optical absorption and photoluminescence measurements were p
Synthesis and Evaluation of Coumarin-Resveratrol Hybrids as 15-Lipoxygenaze Inhibitors
Rahmani-Nezhad, Samira,Khosravani, Leila,Saeedi, Mina,Divsalar, Kouros,Firoozpour, Loghman,Pourshojaei, Yaghoub,Sarrafi, Yaghoub,Nadri, Hamid,Moradi, Alireza,Mahdavi, Mohammad,Shafiee, Abbas,Foroumadi, Alireza
supporting information, p. 751 - 759 (2015/10/29)
A series of coumarin-resveratrol hybrids, 3-arylcoumarin derivatives 3a-u, were synthesized through the intermolecular condensation reaction of various salicylaldehydes and phenylacetic acids in the presence of 1,4-diazabicyclo[2.2.2]octane under solvent-free conditions. All the synthesized compounds were screened for their inhibitory potency against soybean 15-lipoxygenase. Among them, three compounds (3c, 3j, and 3q) showed good enzyme-inhibitory activities. GRAPHICAL ABSTRACT.
Coumarins: Fast Synthesis by Knoevenagel Condensation under Microwave Irradiation
Bogdal, Dariusz
, p. 468 - 469 (2007/10/03)
Condensation of salicyaldehyde or its derivatives with various derivatives of ethyl acetate in the presence of piperidine leads to the synthesis of coumarins by a solvent free reaction under microwave irradiation.
