17324-35-5

Upstream product

• 4091-39-8 3-chloro-2-butanone 
• 100-66-3 methoxybenzene 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 67-66-3 chloroform 
• 7789-60-8 phosphorus tribromide 
• 56-23-5 tetrachloromethane 
• 22927-05-5 3,3-bis-(4-methoxy-phenyl)-butan-2-one 
• 13366-36-4 trans-2,3-bis(4-hydroxyphenyl)-2-butene 
• 77-78-1 dimethyl sulfate 
• 503-17-3 dimethylacetylene 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 65026-54-2 d,l-2,3-bis(4-methoxyphenyl)butane 
• 15624-00-7 (+/-)-threo-2-<4-(2-Diethylamino-ethoxy)-phenyl>-3-(4-hydroxy-phenyl)-butan 
• 15515-43-2 (+/-)-erythro-2-<4-(2-Dimethylamino-ethoxy)-phenyl>-3-(4-methoxy-phenyl)-butan 
• 2962-14-3 racem.-2,3-bis-(4-hydroxy-phenyl)-butane 
• 99553-77-2 (3S,5S)-3,5-Bis-(4-methoxy-phenyl)-3,5-dimethyl-[1,2,4]trioxolane 
• 99553-77-2 (3R,5S)-3,5-Bis-(4-methoxy-phenyl)-3,5-dimethyl-[1,2,4]trioxolane 
• 99553-75-0 trans-2,3-bis(4'-methoxyphenyl)-2,3-dimethyloxirane 
• 13366-36-4 trans-2,3-bis(4-hydroxyphenyl)-2-butene 
• 15542-17-3 4-[2-(4-methoxy-phenyl)-1-methyl-propenyl]-phenol 

Relevant academic research and scientific papers

A heterobimetallic complex featuring a Ti-Co multiple bond and its application to the reductive coupling of ketones to alkenes

To explore metal-metal multiple bonds between first row transition metals, Ti/Co complexes supported by two phosphinoamide ligands have been synthesized and characterized. The Ti metalloligand Cl2Ti(XylNPiPr2)2 (1) was treated with CoI2 under reducing conditions, permitting isolation of the Ti/Co complex [(μ-Cl)Ti(XylNPiPr2)2CoI]2 (2). One electron reduction of complex 2 affords ClTi(XylNPiPr2)2CoPMe3 (3), which features a metal-metal triple bond and an unprecedentedly short Ti-Co distance of 2.0236(9) ?. This complex is shown to promote the McMurry coupling reaction of aryl ketones into alkenes, with concomitant formation of the tetranuclear complex [Ti(μ3-O)(NXylPiPr2)2CoI]2 (4). A cooperative mechanism involving bimetallic C=O bond activation and a cobalt carbene intermediate is proposed.

Ionic-liquid-influenced expeditious and stereoselective synthesis of olefins

1-Butyl-3-methylimidazolium chloroaluminate, [bmim]Cl·.AlCl3 (molar fraction, N=0.67), ionic liquid has been used in combination with metallic Zn for the reductive coupling of carbonyl compounds to synthesize symmetrical olefins, with the Z-isomer formed predominantly. The ionic liquid played a dual role of Lewis acid catalyst and solvent. Copyright Taylor & Francis Group, LLC.

SiCl4-Zn induced reductive coupling of carbonyl compounds: novel and efficient routes for one-pot syntheses of 1,2,3-triaryl-2-propen-1-ones and pinacolones at room temperature

An unprecedented one-pot reductive trimerization of aromatic aldehydes to 1,2,3-triaryl-2-propen-1-ones as well as tandem reductive coupling-rearrangements of aryl ketones to pinacolone analogues was efficiently achieved using tetrachlorosilane-zinc at room temperature.

Stereochemistry and Side Products in Reductive Coupling of Alkyl Aryl Ketones to 1,2-Dialkyl-1,2-diarylethylenes

The reductive coupling of alkyl aryl ketones 1 - 3 and 7 - 9 by low valent titanium salts yields predominantly the (Z)-isomers of 11 - 13 and 17 - 19.Evidence is given by 1H NMR spectroscopy.This behavior can be explained by ?-complex formation of phenyl rings with Ti0.Severe steric hindrance, however, favors the (E)-isomers ( -> 14 and 15).Donor groups in p-position, particularly, give increasing amounts of pinacols, 23 - 27, which undergo rearrangement to the ketones 28 and 29.

The mass spectra of diethylstilbestrol and related compounds

The low resolution mass spectra of E-3,4-bis-(p-hydroxyphenyl)-hex-3-ene (diethylstilbestrol), E-[1,1,1-3H3]3,4-bis-(p-hydroxyphenyl)-hex-3-ene, E-2,3-bis-(p-hydroxyphenyl)-but-2-ene (dimethylstilbestrol), E,E-3,4-bis-(p-hydroxyphenyl)hexa-2,4-diene (dienestrol) and 3,4-bis-(p- hydroxyphenyl)-hexane (hexestrol) were examined as the parent compounds, their diacetates, dimethyl ethers, and bis-trimethylsilyl ethers. In addition, the mass spectra of the diethyl ether and the hexadeuteriodimethyl ether of E-3,4-bis-(p-hydroxyphenyl)-hex-3-ene were studied. Each compound gives rise to several sets of characteristic fragment ions associated with loss of alkyl groups, loss of aryl groups and rearrangements. An ion of m/e 165 (C13H9) was found in the spectra of all the compounds studied. With the aid of high resolution mass spectrometry empirical formulae were assigned to major ions of the free diphenols.