173424-86-7

Basic information

• Product Name: 1-Benzyl-7-[6-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzo[1,3]dioxol-5-yl]-2,3-dihydro-1H-indole
• CAS NO: 173424-86-7
• Molecular Weight: 426.515
• Mol File: 173424-86-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Benzyl-7-[6-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzo[1,3]dioxol-5-yl]-2,3-dihydro-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-7-[6-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzo[1,3]dioxol-5-yl]-2,3-dihydro-1H-indole(173424-86-7)
• EPA Substance Registry System: 1-Benzyl-7-[6-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzo[1,3]dioxol-5-yl]-2,3-dihydro-1H-indole(173424-86-7)

Safety Data

• Hazardous Substances Data: 173424-86-7(Hazardous Substances Data)

Upstream product

• 62813-85-8 7-bromo-2,3-dihydroindole 
• 100-39-0 benzyl bromide 

Downstream Products

• 52886-06-3 hippadine 
• 40360-71-2 anhydrolycorine-7-one 

Relevant articles and documents

An oxazoline-mediated synthesis of the pyrrolophenanthridine alkaloids and some novel derivatives

An unsymmetrical biaryl coupling between the Grignard of N-benzyl-7-bromoindoline 25 and the appropriately substituted (o-methoxyaryl)oxazoline 15 leads to an intermediate biaryl which can be elaborated in one step to the 1H-pyrrolo[3,2,1-de]phenanthridine ring system. This simple two-step sequence provides general access to the pyrrolophenanthridine alkaloids 2-6.