17345-68-5Relevant articles and documents
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Singh,J.M.
, p. 1168 - 1169 (1968)
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Design and synthesis of new curcuminoid compounds and their derivatives as antioxidant agents
Abood, Rehab G.,Alsalim, Tahseen A.,Abood, Einas A.
, p. 2173 - 2183 (2021/04/22)
A series of new curcumin analogues and their derivatives were synthesized by reacting curcumin analogues with various substituted hydrazine compounds to afford new pyrazol derivatives. The preparation of ether and ester derivatives was also carried out. All synthesized compounds were characterized using FT-IR, 1HNMR, 13CNMR, and MS-ESI. The evaluations of these compounds have shown a good inhibition activity as antioxidant agents against the stable radical of diphenylpicrylhydrazyl (DPPH). Findings from this work demonstrated a high inhibition activity in compounds substituted with hydroxyl phenol groups in comparison with compounds with other groups.
A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones as inhibitors of chorismate synthase
Thomas, Michael G.,Lawson, Chris,Allanson, Nigel M.,Leslie, Bruce W.,Bottomley, Joanna R.,McBride, Andrew,Olusanya, Oyinkan A.
, p. 423 - 426 (2007/10/03)
A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones was identified as potent inhibitors of bacterial chorismate synthase. The 2′-hydroxy-4′-pentoxy analogue 33 is a potent inhibitor of Streptococcus pneumoniae chorismate synthase.
