17357-38-9

Basic information

• Product Name: Furan-2-carbothioic acid S-phenyl ester
• Synonyms: 2-Furancarbothioic acid S-phenyl ester;Furan-2-carbothioic acid S-phenyl ester;Furan-2-thiocarboxylic acid S-phenyl ester
• CAS NO: 17357-38-9
• Molecular Formula: C₁₁H₈O₂S
• Molecular Weight: 0
• Mol File: 17357-38-9.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 292.4°C at 760 mmHg
• Flash Point: 130.6°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 0.00184mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: Furan-2-carbothioic acid S-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Furan-2-carbothioic acid S-phenyl ester(17357-38-9)
• EPA Substance Registry System: Furan-2-carbothioic acid S-phenyl ester(17357-38-9)

Safety Data

• Hazardous Substances Data: 17357-38-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H8O2S/c12-11(10-7-4-8-13-10)14-9-5-2-1-3-6-9/h1-8H

Upstream product

• 527-69-5 2-furancarbonyl chloride 
• 108-98-5 thiophenol 
• 88-14-2 2-furanoic acid 
• 144223-33-6 2-furoyl-1H-1,2,3-benzotriazole 
• 882-33-7 diphenyldisulfane 
• 98-01-1 furfural 
• 98-00-0 (2-furyl)methyl alcohol 
• 615-08-7 2-furoic anhydride 
• 56-23-5 tetrachloromethane 
• 124-38-9 carbon dioxide 
• 94-36-0 dibenzoyl peroxide 
• 873-55-2 sodium benzenesulfonate 

Downstream Products

• 1929-89-1 furan-2-carboxylic acid phenylamide 
• 16003-14-8 2-phenylthiofuran 
• 161497-69-4 (furan-2-yl)(dimethyl(phenyl)silyl)methanone 
• 59014-94-7 phenyl dithio-2-furoate 
• 98-00-0 (2-furyl)methyl alcohol 

Relevant articles and documents

Dess-Martin periodinane mediated synthesis of thioesters from aldehydes

Dess-Martin periodinane (DMP) mediated efficient synthesis of thioesters from the corresponding aldehydes under mild conditions is described.

Thioesterification and Selenoesterification of Amides via Selective N-C Cleavage at Room Temperature: N-C(O) to S/Se-C(O) Interconversion

The direct nucleophilic addition to amides represents an attractive methodology in organic synthesis that tackles amidic resonance by ground-state destabilization. This approach has been recently accomplished with carbon, nitrogen and oxygen nucleophiles.

Imidazolium-supported benzotriazole: an efficient and recoverable activating reagent for amide, ester and thioester bond formation in water

An efficient and recyclable imidazolium-supported benzotriazole reagent (Im-CH2-BtH) as a novel synthetic auxiliary has been synthesized and its utility as a carboxyl group activating reagent via the formation of stable imidazolium-supported acyl benzotriazoles was explored for the synthesis of amides, esters and thioesters in water under microwave conditions. The reagent was reused five times without any noticeable loss in activity. It is moisture insensitive and highly stable under thermal and aerobic conditions. The application of imidazolium-supported N-acetyl benzotriazole leads to synthesis of paracetamol on the gram scale under greener conditions in 93% yield.