173597-01-8Relevant articles and documents
Studies on agents with vasodilator and β-blocking activities. III synthesis and activity of optical isomers of TZC-1370
Seki,Takezaki,Ohuchi,Saitoh,Ishimori,Yasuda
, p. 1719 - 1723 (2007/10/03)
Optical isomers of TZC-1370 (1) were prepared from (R)- and (S)-1-(2- chlorophenoxy)-2,3-epoxypropane. When given intravenously to anesthetized rats, the (S)-isomer was about 40 times more potent in terms of β-blocking activity than the (R)-isomer, while