128994-25-2

Basic information

• Product Name: (S)-2-((2-CHLOROPHENOXY)METHYL)OXIRANE
• Synonyms: (S)-2-((2-CHLOROPHENOXY)METHYL)OXIRANE
• CAS NO: 128994-25-2
• Molecular Formula: C₉H₉ClO₂
• Molecular Weight: 184.61956
• Mol File: 128994-25-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-2-((2-CHLOROPHENOXY)METHYL)OXIRANE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((2-CHLOROPHENOXY)METHYL)OXIRANE(128994-25-2)
• EPA Substance Registry System: (S)-2-((2-CHLOROPHENOXY)METHYL)OXIRANE(128994-25-2)

Safety Data

• Hazardous Substances Data: 128994-25-2(Hazardous Substances Data)

Usage

General Description

(S)-2-((2-chlorophenoxy)methyl)oxirane, also known as (S)-2-(2-chlorophenoxy)propylene oxide, is a chemical compound that contains a chlorophenyl group and an epoxide functional group. It is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. (S)-2-((2-CHLOROPHENOXY)METHYL)OXIRANE is a chiral molecule, meaning it has a non-superimposable mirror image, and its enantiomers may have different biological activities. It is important to handle and store (S)-2-((2-chlorophenoxy)methyl)oxirane with care, as it can be irritating to the skin, eyes, and respiratory system. Additionally, it may pose environmental hazards if not managed properly.

Upstream product

• 95-57-8 2-monochlorophenol 
• 57044-25-4 (R)-oxiranemethanol 
• 2212-04-6 1-(2-chlorophenoxy)-2,3-epoxypropane 
• 124-38-9 carbon dioxide 
• 173597-01-8 (R)-4-(2-Chloro-phenoxymethyl)-2,2-dimethyl-[1,3]dioxolane 
• 173597-02-9 Toluene-4-sulfonic acid (R)-3-(2-chloro-phenoxy)-2-hydroxy-propyl ester 
• 115314-14-2 (R)-glycidyl nosylate 
• 115314-14-2 (2s)-(+)-glycidyl 3-nitrobenzenesulfonate 
• 148552-91-4 (S)-3-(2-chlorophenoxy)propane-1,2-diol 

Downstream Products

• 282099-34-7 2-(4-{3-hydroxy-(2S)-2-[(2S)-2-hydroxy-3-(2-chlorophenoxy) propylamino]-propyl}phenoxy)nicotinamide 

Relevant articles and documents

Chiral Bifunctional Metalloporphyrin Catalysts for Kinetic Resolution of Epoxides with Carbon Dioxide

Chiral binaphthyl-strapped Zn(II) porphyrins with triazolium halide units were synthesized as bifunctional catalysts for kinetic resolution of epoxides with CO2. Several catalysts were screened by changing the linker length and nucleophilic counteranions, and the optimized catalyst accelerated the enantioselective reaction at ambient temperature to produce optically active cyclic carbonates and epoxides.

LIGANDS FOR CARDIAC BETA1 ADRENOCEPTOR FOR IMAGING CONGESTIVE HEART FAILURE

Novel β1 adrenoreceptor ligands that find use as imaging agents within nuclear medicine applications (e.g., PET imaging and SPECT imaging) are provided. Methods of imaging, including methods of imaging congestive heart failure, are also provide

Studies on agents with vasodilator and β-blocking activities. III synthesis and activity of optical isomers of TZC-1370

Optical isomers of TZC-1370 (1) were prepared from (R)- and (S)-1-(2- chlorophenoxy)-2,3-epoxypropane. When given intravenously to anesthetized rats, the (S)-isomer was about 40 times more potent in terms of β-blocking activity than the (R)-isomer, while