173777-89-4

Basic information

• Product Name: 2,5-DICHLOROTHIOPHENE
• Synonyms: DICHLOROTHIOPHENE;2,6-DICHLOROTHIOPHENE;2,5-Dichlorothiophene, 96.0%(GC)
• CAS NO: 173777-89-4
• Molecular Formula: C4H2Cl2S
• Molecular Weight: 153.03
• EINECS: 221-638-8
• Product Categories: Sulphur Derivatives
• Mol File: 173777-89-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 158.9 °C at 760 mmHg
• Flash Point: 59.4 °C
• Appearance: /
• Density: 1.488 g/cm³
• Vapor Pressure: 3.33mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 2,5-DICHLOROTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DICHLOROTHIOPHENE(173777-89-4)
• EPA Substance Registry System: 2,5-DICHLOROTHIOPHENE(173777-89-4)

Safety Data

• Hazard Codes: T+:Very toxic
• Statements: R26/27/28:; R40:
• Safety Statements: S28A:; S36/37:; S45:
• Hazardous Substances Data: 173777-89-4(Hazardous Substances Data)

Usage

General Description

2,5-Dichlorothiophene is a chemical compound with the molecular formula C4H2Cl2S. It is a colorless to light yellow liquid with a pungent odor. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 2,5-Dichlorothiophene is also used as a building block in the production of complex organic molecules and as a reagent in chemical research. It is classified as a hazardous chemical and should be handled with care and in accordance with proper safety protocols.

InChI:InChI=1/C4H2Cl2S/c5-3-1-2-4(6)7-3/h1-2H

Upstream product

• 188290-36-0 thiophene 
• 598-49-2 N-chloroacetamide 
• 96-43-5 2-thienyl chloride 
• 18243-72-6 2-(methyldichlorosilyl)thiophene 
• 18145-51-2 trichloro-thiophen-2-yl-silane 
• 36157-41-2 2,5-dichlorothiophene-3-carboxylic acid 
• 64-17-5 ethanol 
• 64048-11-9 2,3,4,5-tetrachloro-tetrahydro-thiophene 
• 7782-50-5 chlorine 
• 18614-15-8 2,2,3,4,5,5-hexachloro-tetrahydro-thiophene 
• 7732-18-5 water 
• 527-72-0 2-thiophenylcarboxylic acid 

Downstream Products

• 99979-31-4 1-(2,5-dichloro-[3]thienyl)-2-phenyl-ethanone 
• 40477-45-0 2,5-dichloro-3,4-dibromothiophene 
• 17019-32-8 2-tert.Butoxy-5-chlorthiophen 
• 61200-60-0 2,5-dichlorothiophene-4-carboxaldehyde 
• 90454-54-9 phenyl N-(2,5,5-trichloro-2,5-dihydro-2-thienyl)-carbamate 
• 90454-56-1 phenyl N-(3,5-dichloro-2-thienyl)-carbamate 
• 32766-64-6 ethyl 2,5-dichloro-3-thienylglyoxylate 
• 56946-83-9 2,5-dichlorothiophene-3-sulfonyl chloride 
• 3988-99-6 bis(thien-2-yl)sulfide 
• 6911-51-9 2-thienyl disulfide 
• 1552295-06-3 4-(2,5-dichlorothiophen-3-yl)benzaldehyde 
• 1552295-07-4 3-(2,5-dichlorothiophen-3-yl)benzonitrile 
• 1552295-08-5 2,5-dichloro-3-(3-nitrophenyl)thiophene 
• 1552295-04-1 1-[4-(2,5-dichlorothiophen-3-yl)phenyl]ethanone 

Relevant articles and documents

Synthesis and structural characterization of 2,5-dihalo-3,4- dinitrothiophenes

Using new nitration protocols, we have been able to efficiently dinitrate 2,5-dihalothiophenes with yields of ～80-95%. The resulting products 2,5-dibromo-3,4-dinitrothiophene (1), 2,5-dichloro-3,4-dinitrothiophene (2), 2-bromo-5-chloro-3,4-dinitrothiophene (3), as well as the analogous 2-bromo-3,4-dinitrothiophene (4), all crystallize easily allowing their characterization via X-ray crystallography. Crystallization of 1 occurs in the monoclinic space group C2/c with a=14.547(3)A, b=7.3534(15)A, c=10.775(2)A, β=128.89(3)°, and Z=4. Crystallization of 2 occurs in the tetragonal space group I-42d with a=9.9398(14)A, b=9.9398(14)A, c=16.866(3)A, and Z=8. Crystallization of 3 occurs as a pseudo-merohedral twin in the triclinic space group P-1 with a=7.340(5)A, b=8.094(5)A, c=9.112(5)A, α=82.059(5)°, β=66.232(5)°, γ=63.021(5)°, and Z=2. Crystallization of 4 occurs in the triclinic space group P-1 with a=7.1787(14)A, b=7.4092(15)A, c=8.3151(17)A, α=101.67(3)°, β=96.00(3)°, γ=116.13(3)°, and Z=2. The structures of all compounds exhibit the formation of interesting solid-state assemblies due to halogen-bonding interactions between the halogen and nitro groups. Springer Science+Business Media, LLC 2007.

2, 5-dichloro thiophene preparation method

The present invention discloses a 2, 5-dichloro thiophene preparation method comprising the following steps: (1) an organic solvent and thiophene are added into a reaction vessel and warmed to reflux, under reflux conditions, batches of added N-chlorosucc

Halogenation of Aromatic Compounds by N-chloro-, N-bromo-, and N-iodosuccinimide

An efficient and mild method for the halogenation of aromatic compounds using N-chloro-, N-bromo-, and N-iodosuccinimide in the presence of NH 4NO3 or FeCl3 in acetonitrile was developed.