17381-54-3

Basic information

• Product Name: Benzo[b]thiophene-5-acetic acid
• Synonyms: Benzo[b]thiophene-5-acetic acid
• CAS NO: 17381-54-3
• Molecular Formula: C₁₀H₈O₂S
• Molecular Weight: 192.23432
• EINECS: -0
• Mol File: 17381-54-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzo[b]thiophene-5-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophene-5-acetic acid(17381-54-3)
• EPA Substance Registry System: Benzo[b]thiophene-5-acetic acid(17381-54-3)

Safety Data

• Hazardous Substances Data: 17381-54-3(Hazardous Substances Data)

Usage

Uses

Benzo[b]thiophene-5-acetic Acid is derived from 5-Bromobenzo[b]thiophene (B680425), which is used as a reactant in the preparation of 4-aminoquinolines and tetraoxanes displaying antimalarial activity.

Upstream product

• 143-33-9 sodium cyanide 
• 10133-22-9 5-bromomethyl-benzo[b]thiophene 
• 911472-13-4 tert-butyl 2-(1-benzothiophen-5-yl)-2-cyanoacetate 
• 911472-12-3 ethyl 2-(1-benzothiophen-5-yl)-2-cyanoacetate 
• 911472-11-2 2-(1-benzothiophen-5-yl)malonic acid 
• 17381-51-0 (1-benzothiophen-5-yl)acetonitrile 
• 186581-53-3 diazomethane 
• 2060-64-2 benzo[b]thiophene-5-carboxylic acid 

Downstream Products

• 349672-87-3 5-(2-(4-Hydroxy-4-(3-trifluoromethylphenyl)piperidino)ethyl)benzothiophene 
• 96803-30-4 5-(2-hydroxyethyl)benzo[b]thiophene 

Relevant articles and documents

TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS

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Structure-activity studies for a novel series of N-(arylethyl)-N- (1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamines possessing dual 5- HT uptake inhibiting and α2-antagonistic activities

In search of an α2-antagonist/5-HT uptake inhibitor as a potential new class of antidepressant with a more rapid onset of action, compound 3 was prepared and observed to possess high affinity for the α2-receptor (K(i) = 6.71 nM) and