17381-54-3 Usage
Uses
Used in Pharmaceutical Industry:
Benzo[b]thiophene-5-acetic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its role in the preparation of 4-aminoquinolines and tetraoxanes is particularly noteworthy, as these compounds have demonstrated antimalarial activity. The development of new antimalarial drugs is crucial in combating drug-resistant strains of the malaria parasite, making Benzo[b]thiophene-5-acetic acid a valuable component in the fight against this global health threat.
Additionally, given its structural similarity to other bioactive compounds, Benzo[b]thiophene-5-acetic acid may also be utilized in the development of new drugs for other therapeutic areas, such as anti-inflammatory, analgesic, or anti-cancer agents. Further research and development in this area could lead to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 17381-54-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,8 and 1 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 17381-54:
(7*1)+(6*7)+(5*3)+(4*8)+(3*1)+(2*5)+(1*4)=113
113 % 10 = 3
So 17381-54-3 is a valid CAS Registry Number.
17381-54-3Relevant academic research and scientific papers
PROCESS FOR PRODUCTION OF 1-(3-(2-(1-BENZOTHIOPHEN-5-YL)- ETHOXY)PROPYL)AZETIDIN-3-OL OR SALTS THEREOF
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Page/Page column 33, (2008/06/13)
A Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which comprises using as a starting compound as a (phenylthio)acetic acid derivative or salts thereof represented by the general formula: wherein X1 represents a halogen atom, is useful as a safe process for mass production of 1-(3-(2-(1- benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which is useful as a remedy for disease of central and peripheral nerve.
Structure-activity studies for a novel series of N-(arylethyl)-N- (1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamines possessing dual 5- HT uptake inhibiting and α2-antagonistic activities
Meyer, Michael D.,Hancock, Arthur A.,Tietje, Karin,Sippy, Kevin B.,Prasad, Rajnandan,Stout, David M.,Arendsen, David L.,Donner, B. Greg,Carroll, William A.
, p. 1049 - 1062 (2007/10/03)
In search of an α2-antagonist/5-HT uptake inhibitor as a potential new class of antidepressant with a more rapid onset of action, compound 3 was prepared and observed to possess high affinity for the α2-receptor (K(i) = 6.71 nM) and
