1740-54-1Relevant academic research and scientific papers
Odd-even effect in melting properties of 12 alkane-α,ω-diamides
Badea, Elena,Gatta, Giuseppe Della,D'Angelo, Domenico,Brunetti, Bruno,Reckova, Zuzana
, p. 1546 - 1552 (2006)
Fusion and solid-to-solid transitions of a homologous series of 12 linear alkane-α,ω-diamides H2NCO-(CH2)(n-2)-CONH2, where n = (2 to 12 and 14), were investigated by differential scanning calorimetry (d.s.c.). The temperatures of fusion of even terms decreased from Tfus ≈ 572 K to about 460 K, whereas those of odd terms remained substantially constant at about 450 K. Solid-to-solid transitions were also detected for oxamide, malonamide, succinamide, adipamide, suberamide, and dodecanediamide. Regular odd-even alternation was displayed by the temperature, enthalpy, and entropy of fusion values, terms with even number of carbon atoms showing higher values than odd terms. This behaviour was attributed to different crystal packing allowing consonance between hydrogen bonding and dispersive interaction in even terms, which are characterised by multilayer structure, whereas in odd terms a strained three-dimensional network results in looser packing. Parallel alternation of densities in solid alkane-α,ω-diamides supports this interpretation. Comparison was made with literature values for temperatures, enthalpies, and entropies of fusion of isoelectronic linear alkanes, dicarboxylic acids, and alkyldiamines.
Method for producing aliphatic diamine (by machine translation)
-
Paragraph 0053, (2019/07/05)
[Problem] safety, yield, at least one aliphatic diamine having improved simplicity in terms of the method. (1) Formula (2) represented by the formula [a] or the aliphatic diamide, sodium hypochlorite, the presence of a base, a water and alcohol mixture containing alcohol in a solvent comprises the step of - the reaction, the molar ratio of the aliphatic diamide basic, aliphatic diamide (molar ratio)=1.8 - 6.0 in/base, production of aliphatic diamine. [Drawing] no (by machine translation)
Corresponding amine nitrile and method of manufacturing thereof
-
Paragraph 0124; 0125; 0127, (2018/05/24)
The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.
Corresponding amine nitrile and method of manufacturing thereof (by machine translation)
-
Paragraph 0124; 0125; 0126; 0127, (2018/07/15)
The present invention relates to a nitrile manufacturing method, which has characteristics of significantly-reduced ammonia source consumption, low environmental pressure, low energy consumption, low production cost, high nitrile purity, high nitrile yield and the like compared with the method in the prior art, wherein nitrile having a complicated structure can be obtained through the method. The present invention further relates to a method for producing a corresponding amine from the nitrile.
Corresponding amine nitrile and method of manufacturing thereof
-
Paragraph 0125; 0126; 0127; 0128, (2018/07/15)
The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.
Direct preparation of primary amides by reaction of carboxylic acids and ammonia in alcohols using DMT-MM
Mizuhara, Tsukasa,Hioki, Kazuhito,Yamada, Megumi,Sasaki, Hideaki,Morisaki, Daiki,Kunishima, Munetaka
body text, p. 1191 - 1192 (2009/12/01)
A simple and mild method for the direct conversion of carboxylic acids to primary amides has been developed by using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)- 4-methylmorpholim'um chloride (DMT-MM). The reaction proceeds by adding DMT-MM to a mixture of carboxylic acids and an ammonia source in methanol, 2-propanol, or THF without any additives. The present method is quite practical in that aqueous ammonia or ammonium chloride/triethylarnine can be used as an ammonia source. Methanol or 2-propanol is an ideal polar solvent because it is inexpensive, can be removed by rotary evaporator, and solubilizes many kinds of polar or nonpolar compounds.
STUDY OF THE REACTIVITY OF AMMONIUM CARBOXYLATES IN THE SYNTHESIS OF AMIDES UNDER HIGH-PRESSURE DEFORMATION CONDITIONS
Christotina, N. P.,Zharov, A. A.
, p. 2103 - 2106 (2007/10/02)
On deformation under pressures up to 10 GPa the ammonium salts of aliphatic and aromatic acids, as well as mixtures of a free carboxylic acid with the ammonium salts of strong mineral acids, are converted into the corresponding amides.The amide yields increase with pressure, the magnitude of shearing deformation, and temperature.The temperature and pressure coefficients for amide formation are low and have values of 2.5-4 kJ/mole and -1 to -2 cm3/mole, respectively.The reactivity of ammonium salts in the synthesis of amides alternates in the homologous series of aliphatic acids in a similar way to the shear stress of these salts.The reactivity of the ammonium salts of aliphatic acids increases when the reaction is conducted in a matrix of an ammonium salt which possesses plasticity and a high shear stress.
