174422-23-2

Basic information

• Product Name: Benzoic acid, 3-amino-4-[[(4-chlorophenyl)methyl]amino]-, methyl ester
• CAS NO: 174422-23-2
• Molecular Formula: C15H15ClN2O2
• Molecular Weight: 290.749
• Mol File: 174422-23-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-amino-4-[[(4-chlorophenyl)methyl]amino]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-amino-4-[[(4-chlorophenyl)methyl]amino]-, methyl ester(174422-23-2)
• EPA Substance Registry System: Benzoic acid, 3-amino-4-[[(4-chlorophenyl)methyl]amino]-, methyl ester(174422-23-2)

Safety Data

• Hazardous Substances Data: 174422-23-2(Hazardous Substances Data)

Upstream product

• 174422-22-1 methyl 4-(4-chlorobenzylamine)-3-nitrobenzoic acid ester 
• 14719-83-6 methyl 3-nitro-4-chlorobenzoate 
• 96-99-1 4-chloro-3-nitrobenzoate 
• 104-86-9 4-chlorobenzylamine 

Downstream Products

• 355022-45-6 2-(4-carboxy-phenyl)-1-(4-chloro-benzyl)-1H-benzoimidazole-5-carboxylic acid methyl ester 
• 1168139-13-6 methyl 1-(4-chlorobenzyl)-1H-benzo[d]imidazole-5-carboxylate 
• 1168139-12-5 methyl 1-[(4-chlorophenyl)methyl]-2-methyl-1H-benzimidazole-5-carboxylate 
• 1096969-16-2 1-[(4-chlorophenyl)methyl]-2-methyl-1H-benzimidazole-5-carboxylic acid 
• 1168138-16-6 1-[(4-chlorophenyl)methyl]-2-methyl-N-[(1R)-1-phenylpropyl]-1H-benzimidazole-5-carboxamide 
• 1393711-18-6 methyl 1-(4-chlorobenzyl)-2-(3,4-dichlorophenyl)-1H-benzimidazole-5-carboxylate 
• 1002322-47-5 methyl 1-(p-chlorobenzyl)-2-phenyl-1H-benzimidazole-5-acetate 
• 174422-21-0 1-(4-Chloro-benzyl)-2-(2,4-dichloro-phenyl)-1H-benzoimidazole-5-carboxylic acid 
• 174422-20-9 1-(4-Chloro-benzyl)-2-(4-chloro-phenyl)-1H-benzoimidazole-5-carboxylic acid 
• 214903-74-9 1-(4-Chloro-benzyl)-2-(4-methyl-piperazin-1-yl)-1H-benzoimidazole-5-carboxylic acid methyl ester 
• 214903-76-1 1-(4-Chloro-benzyl)-2-(4-methyl-piperazin-1-yl)-1H-benzoimidazole-5-carboxylic acid 
• 214903-71-6 2-Chloro-1-(4-chloro-benzyl)-1H-benzoimidazole-5-carboxylic acid methyl ester 

Relevant articles and documents

Heterocyclic derivative and pharmaceutical composition comprising the same

The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect. A pharmaceutical composition having a P2X3 and/or P2X2/3 receptor antagonistic effect comprising a compoun

Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist

The peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated nuclear receptor, thought to play a role in energy metabolism, glucose homeostasis and microglia-mediated neuroinflammation. A novel benzimidazole series of centrally penetrant PPARγ partial agonists has been identified. The optimization of PPARγ activity and in vivo pharmacokinetics leading to the identification of GSK1997132B a potent, metabolically stable and centrally penetrant PPARγ partial agonist, is described.

Synthesis and antioxidant capacities of some new benzimidazole derivatives

In this study, we prepared some new oxadiazolyl benzimidazole derivatives and investigated their antioxidant properties by determination of microsomal NADPH-dependent inhibition of lipid peroxidation levels (LP assay) and microsomal ethoxyresorufin O-deet