174744-18-4

Basic information

• Product Name: ALPHA-TRIFLUOROMETHYL-BETA-BUTYROLACTONE
• Synonyms: ALPHA-TRIFLUOROMETHYL-BETA-BUTYROLACTONE;alpha-trifluoromethyl-gamma-bu;ALPHA-TRIFLUOROMETHYL-GAMMA-BUTYROLACTONE,95%;2-Oxo-3-(trifluoromethyl)tetrahydrofuran, 3-(Trifluoromethyl)oxolan-2-one, alpha-(Trifluoromethyl)-gamma-butyrolactone;3-(Trifluoromethyl)dihydrofuran-2(3H)-one
• CAS NO: 174744-18-4
• Molecular Formula: C₅H₅F₃O₂
• Molecular Weight: 154.09
• Mol File: 174744-18-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 50 °C (0.2 mmHg)
• Flash Point: 85.2°C
• Appearance: /
• Density: 1.409g/cm³
• Vapor Pressure: 0.914mmHg at 25°C
• Refractive Index: 1.374
• CAS DataBase Reference: ALPHA-TRIFLUOROMETHYL-BETA-BUTYROLACTONE(CAS DataBase Reference)
• NIST Chemistry Reference: ALPHA-TRIFLUOROMETHYL-BETA-BUTYROLACTONE(174744-18-4)
• EPA Substance Registry System: ALPHA-TRIFLUOROMETHYL-BETA-BUTYROLACTONE(174744-18-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• Hazardous Substances Data: 174744-18-4(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow liquid after melting

InChI:InChI=1/C5H5F3O2/c6-5(7,8)3-1-2-10-4(3)9/h3H,1-2H2/t3-/m0/s1

Upstream product

• 1414364-03-6 ethyl 4-hydroxy-2-(trifluoromethyl)butanoate 
• 21441-31-6 3-(bis-methylsulfanyl-methylene)-dihydro-furan-2-one 
• 67-56-1 methanol 
• 381-98-6 trifluoromethyacrylic acid 

Downstream Products

• 501368-41-8 N-(4-Benzoylphenyl)-3-trifluoromethylpyrrolidin-2-one 
• 501368-48-5 N-(4-benzoylphenyl)-4-hydroxy-2-trifluoromethylbutanamide 

Relevant articles and documents

Efficient synthesis of new fluorinated building blocks by means of hydroformylation

Hydroformylation of fluorinated alkenes is an efficient method for the preparation of fluorinated functionalized building blocks for the synthesis of biologically active target structures. In this article we summarize known hydroformylation reactions of f

The first general method for α-trifluoromethylation of carboxylic acids using BrF3

2-Carbomethoxy-1,1-bis(methylsulfide)-1-alkenes, easily made from carboxylic acids, CS2 and MeI, were treated with BrF3 producing eventually the desired α-trifluoromethyl carboxylate derivatives - RCH(CF3)COOR′ - in good yields.