174871-36-4

Upstream product

• 124-41-4 sodium methylate 
• 174871-34-2 4-chloro-2-phenyl-5,7-dihydrothieno<3,4-d>pyrimidine 6,6-dioxide 
• 5719-24-4 2-phenyl-3H-5,7-dihydrothieno<3,4-d>pyrimidin-4-one 
• 5719-13-1 4-chloro-2-phenyl-5,7-dihydrothieno<3,4-d>pyrimidine 

Relevant academic research and scientific papers

Pyrimidine ortho-quinodimethanes

The pyrimidine sulfones 10, R = Me; Nu = OMe, NEt2, SPh, H and 11, R = Ph; Nu = OMe were synthesised from the dihydrothienopyrimidones 7, R = Me, Ph by conversion to the chloro derivatives 8 followed by oxidation with mCPBA and reaction with the appropriate nucleophile or hydrogen and Pd. Heating of the sulfones in 1,2,4-trichlorobenzene gave the pyrimidine o-quinodimethanes which were intercepted in Diels-Alder reactions to give tetrahydroquinazolines.