174873-81-5 Usage
General Description
1-Chloro-8-methylisoquinoline, also known as 8-chloro-1-methylisoquinoline, is a chemical compound with a molecular formula C10H8ClN. It is a derivative of isoquinoline, which is a heterocyclic compound. This chemical is used in the field of organic synthesis and pharmaceutical research due to its unique structure and potential biological activities. It may be used as a building block in the synthesis of various organic compounds, such as pharmaceutical drugs and agrochemicals. Its molecular structure consists of an isoquinoline ring system with a chlorine atom at the 8th position and a methyl group at the 1st position, making it a valuable and versatile compound in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 174873-81-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,8,7 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 174873-81:
(8*1)+(7*7)+(6*4)+(5*8)+(4*7)+(3*3)+(2*8)+(1*1)=175
175 % 10 = 5
So 174873-81-5 is a valid CAS Registry Number.
174873-81-5Relevant articles and documents
Synthesis and resolution of 1,1-bi-8-methylisoquinoline: Formation of an optically active complex with high chiral recognition
Chelucci, Giorgio,Cabras, M. Antonietta,Saba, Antonio,Sechi, Alessandra
, p. 1027 - 1032 (1996)
The synthesis and resolution of 1,1-bi-8-methylisoquinoline (±)-5 is reported. An optically active palladium complex with high chiral recognition was formed during the complexation between a chiral palladium complex and the two enantiomers of (±)-5. The free energy barrier ΔGF(≠) for interconversion of enantiomers was estimated to be 97,2 KJ/mol at 40°C.
Preparation of optically active 8,8′-disubstituted 1,1′-biisoquinoline
Hirao, Ken-Ichi,Tsuchiya, Ryuta,Yano, Yasuhiro,Tsue, Hirohito
, p. 415 - 422 (2007/10/02)
Synthesis of 1,1′-biisoquinolines having substituents in the 8,8′-positions and their resolution by hplc on a chiral column on a preparative scale are described.