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1-(benzenesulfinylmethyl)-4-chloro-benzene is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

17530-80-2

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17530-80-2 Usage

Molecular weight

252.7 g/mol

Physical state

White solid

Uses

a. Intermediate in the synthesis of pharmaceuticals and agrochemicals
b. Production of dyes and pigments
c. Reagent in organic chemistry reactions

Applications in organic chemistry

a. Formation of carbon-carbon bonds
b. Formation of carbon-sulfur bonds

Health effects

Potential for both acute and chronic health effects if not handled properly

Safety measures

Importance of using appropriate safety measures when working with this chemical

Check Digit Verification of cas no

The CAS Registry Mumber 17530-80-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,5,3 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17530-80:
(7*1)+(6*7)+(5*5)+(4*3)+(3*0)+(2*8)+(1*0)=102
102 % 10 = 2
So 17530-80-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H11ClOS/c14-12-8-6-11(7-9-12)10-16(15)13-4-2-1-3-5-13/h1-9H,10H2

17530-80-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(benzenesulfinylmethyl)-4-chlorobenzene

1.2 Other means of identification

Product number -
Other names Phenyl-4-chlor-benzyl-sulfoxid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17530-80-2 SDS

17530-80-2Relevant academic research and scientific papers

Synthesis, spectral characterization, crystal structure and catalytic activity of a novel dioxomolybdenum Schiff base complex containing 4-aminobenzhydrazone ligand: A combined experimental and theoretical study

Ali, Saqib,Ashfaq, Muhammad,Behjatmanesh-Ardakani, Reza,Fallah-Mehrjardi, Mehdi,Kargar, Hadi,Munawar, Khurram Shahzad,Nateghi-Jahromi, Maryam,Tahir, Muhammad Nawaz

, (2021/10/16)

A novel dioxomolybdenum Schiff base complex, [MoO2(L)(H2O)], was synthesized by the reaction of MoO2(acac)2 and an ONO donor Schiff base ligand (H2L: (E)-4-amino-N'-(3-ethoxy-2-hydroxybenzylidene)benz

Molybdenum(VI) complexes with tridentate Schiff base ligands derived from isoniazid as catalysts for the oxidation of sulfides: synthesis, X-ray crystal structure determination and spectral characterization

Kargar, Hadi

, (2021/08/16)

Two new complexes, including [MoO2(L1)(CH3OH)] and [MoO2(L2)(CH3OH)], with tridentate ONO–donor Schiff base ligands (H2L1: (E)-N'-(2-hydroxy-3-methoxybenzylidene)isoni

Experimental and theoretical studies of new dioxomolybdenum complex: Synthesis, characterization and application as an efficient homogeneous catalyst for the selective sulfoxidation

Ashfaq, Muhammad,Behjatmanesh-Ardakani, Reza,Fallah-Mehrjardi, Mehdi,Kargar, Hadi,Munawar, Khurram Shahzad,Tahir, Muhammad Nawaz

, (2021/08/23)

A new dioxomolybdenum(VI) complex with tridentate ONO-donor Schiff base ligand derived from isoniazid has been synthesized and characterized by elemental analyses, FT-IR and 1H NMR, and its solid state structure was confirmed by single crystal

Modification of magnetic nanoparticles surface by oxovanadium(V) complex as a highly efficient heterogeneous nanocatalyst for the green sulfoxidation of sulfides

Fallah-Mehrjardi, Mehdi,Kargar, Hadi

, (2021/10/27)

The present study describes the synthesis of a new nanomagnetic-supported oxovanadium(V) complex with the tridentate Schiff base ligand derived from the condensation reaction between 5-bromosalicylaldehyde and nicotinic acid hydrazide. The supported compl

Palladium/PC-Phos-Catalyzed Enantioselective Arylation of General Sulfenate Anions: Scope and Synthetic Applications

Wang, Lei,Chen, Mingjie,Zhang, Peichao,Li, Wenbo,Zhang, Junliang

, p. 3467 - 3473 (2018/03/13)

Herein we reported an efficient palladium-catalyzed enantioselective arylation of both alkyl and aryl sulfenate anions to deliver various chiral sulfoxides in good yields (up to 98%) with excellent enantioselectivities (up to 99% ee) by the use of our developed chiral O,P-ligands (PC-Phos). PC-Phos are easily prepared in short steps from inexpensive commercially available starting materials. The single-crystal structure of the PC4/PdCl2 showed that a rarely observed 11-membered ring was formed via the O,P-coordination with the palladium(II) center. The salient features of this method include general substrate scope, ease of scale-up, applicable to the late-stage modification of bioactive compounds, and the synthesis of a marketed medicine Sulindac.

Synthesis of: N -alkylated 2-pyridones through Pummerer type reactions of activated sulfoxides and 2-fluoropyridine derivatives

Hu, Gang,Xu, Jiaxi,Li, Pingfan

, p. 4151 - 4158 (2018/06/12)

N-Alkylated 2-pyridone products were obtained in good to excellent yields through a one-pot procedure involving either normal or interrupted Pummerer reactions between triflic anhydride activated sulfoxides and 2-fluoropyridine derivatives, followed by hydrolysis. This is a rare case that uses 2-fluoropyridine as a nucleophile in Pummerer type reactions.

Photosensitized oxidation of aryl benzyl sulfoxides. Evidence for nucleophilic assistance to the c-s bond cleavage of aryl benzyl sulfoxide radical cations

Del Giacco, Tiziana,Lanzalunga, Osvaldo,Lapi, Andrea,Mazzonna, Marco,Mencarelli, Paolo

, p. 2310 - 2318 (2015/09/08)

The radical cations of a series of aryl benzyl sulfoxides (4-X-C6H4CH2SOC6H4Y+?) have been generated by photochemical oxidation of the parent sulfoxides sensitized by 3-cyano-N-methylquinolinium perchlorate (3-CN-NMQ+ClO4-). Steady-state photolysis experiments showed the prevailing formation of benzylic products deriving from the C-S fragmentation in the radical cations, together with sulfur-containing products. Formation of sulfoxide radical cations was unequivocally established by laser flash photolysis experiments showing the absorption bands of 3-CN-NMQ? (λmax = 390 nm) and of the radical cations (λmax = 500-620 nm). The decay rate constants of radical cations, determined by LFP experiments, decrease by increasing the electron-donating power of the arylsulfinyl Y substituent and to a smaller extent by increasing the electron-withdrawing power of the benzylic X substituent. A solvent nucleophilic assistance to the C-S bond cleavage has been suggested, supported by the comparison of substituent effects on the same process occurring in aryl tert-butyl sulfoxide radical cations. DFT calculations, performed to determine the bond dissociation free energy in the radical cations, the transition state energies associated with the unimolecular C-S bond cleavage, and the charge and spin delocalized on their structures, were also useful to endorse the nucleophilic assistance to the C-S scission.

Palladium-catalyzed direct arylation of methyl sulfoxides with aryl halides

Jia, Tiezheng,Bellomo, Ana,Baina, Kawtar El,Dreher, Spencer D.,Walsh, Patrick J.

supporting information, p. 3740 - 3743 (2013/04/10)

The palladium-catalyzed α-arylation of unactivated sulfoxides has been developed. The weakly acidic α-protons of sulfoxides are reversibly deprotonated by LiOtBu, and a palladium phosphine complex facilitates the arylation. A variety of aryl methyl sulfoxides were coupled with aryl bromides. More challenging coupling partners, such as alkyl methyl sulfoxides (including dimethyl sulfoxide) and aryl chlorides proved to be suitable under the optimized conditions. This method was utilized to synthesize bioactive benzyl sulfoxide intermediates.

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