175350-44-4

Upstream product

• 6296-54-4 ethyl 2,4-dioxo-4-phenylbutyrate 
• 538-51-2 benzylidene phenylamine 
• 5817-92-5 2,4-dioxo-4-phenylbutanoic acid 
• 64-17-5 ethanol 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 20577-73-5 methyl 4-phenyl-2,4-dioxobutanoate 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 742-43-8 1,3-diphenyl-3-(N-phenylamino)propanone 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 108784-21-0 3,4,5-Triphenyl-4,5-dihydro-2H-pyrrolo[3,4-c]pyrazol-6-one 
• 108784-15-2 4-Benzoyl-3-hydrazono-1,5-diphenyl-pyrrolidin-2-one 
• 108784-04-9 C₄₈H₃₈N₄O₄ 
• 108784-10-7 5,6,7-Triphenyl-2,3,6,7-tetrahydro-1H-pyrrolo[3,4-e][1,4]diazepin-8-one 
• 108783-98-8 4-Benzoyl-3-(2-hydroxy-ethylamino)-1,5-diphenyl-1,5-dihydro-pyrrol-2-one 

Relevant academic research and scientific papers

A study on the condensation of α,γ-diketoesters with Schiff bases

Condensation of the title compounds 1 with aldimines afforded the 2,3-pyrrolidinediones 2. Compounds 4 and 5 were obtained from 1, nicotinaldehyde and appropriate amine. Whereas, the pyrrolo-benzopyran 7 was obtained from 1 and o-hydroxybenzal-p-toluidine. The condensation of 1b or c with isatine-anil (8) gave the spirocyclic system 10. The bis-ketimine (11) reacts with 1c to give the pyrazinone 13. Treatment of the polyketone 14 with aldimines afforded the 4,5-(1H)-azepinediones (16).

CHEMISTRY OF OXALYL DERIVATIVES OF METHYL KETONES. XLIV. SYNTHESIS OF 4-AROYL-1,5-DIPHENYLTETRAHYDROPYRROLE-2,3-DIONES AND THEIR REACTION WITH AMINES AND HYDRAZINE

The reaction of 4-aroyl-1,5-diphenyltetrahydropyrrole-2,3-diones, obtained from aroylpyruvic esters, benzaldehyde, and aniline, with butylamine and ethylanolamine gave 4-aroyl-3-R-amino-1,5-diphenyl-2,5-dihydropyrrol-2-ones.The reaction with ethylenediami