175609-72-0Relevant academic research and scientific papers
Metalated Fluoropyridines and Fluoroquinolines as Reactive Intermediates: New Ways for Their Regioselective Generation
Shi, Guo-qiang,Takagishi, Sadahito,Schlosser, Manfred
, p. 1129 - 1134 (1994)
The mixture of lithium diisopropylamide and potassium tert-butoxide ("LIDA-KOR reagent") is a powerful base which can be advantageously employed for the regioselective deprotonation of fluoropyridines and, in particular, 3-fluoroquinoline.A novel cyclization process was elaborated for the preparation of the latter product.
