17565-28-5Relevant academic research and scientific papers
α,α-dibromoketones as useful precursors in organic synthesis: A simple and efficient synthesis of 2,4-diaryl- 1,2,3-triazoles via oxidative cyclization of bisphenylhydrazones
Arora, Loveena,Sharma, Nisha,Kapoor, Jitander K.
, p. 291 - 296 (2019/01/18)
α,α-Dibromoacetophenones (1a-1f) on reaction with phenylhydrazine afford corresponding arylglyoxal bisphenylhydrazones (2a-2f). The oxidation of bishydrazones 2a-2f by using copper(II) chloride in acetic acid leads to intramolecular cyclization with the formation of 2,4-diaryl-1,2,3-triazoles (3a-3f). The method for the conversion 1 → 3 has been simplified by developing one-pot procedure without isolation of intermediates 2.
Studies on the Hydrazine Derivatives of p-Tolylglyoxal
El Sadek, Mohamed M.
, p. 357 - 359 (2007/10/02)
A number of p-tolylglyoxalmono- and -bishydrazones were synthesized, acylated, and cyclized to the corresponding 1,2,3-triazoles.Some of the reactions of the prepared triazoles were carried out.Analyses and IR and UV spectra of the compounds prepared were recorded.
