1075-47-4

Basic information

• Product Name: 4-METHYLPHENYLGLYOXAL HYDRATE
• Synonyms: 4-METHYLPHENYLGLYOXAL HYDRATE;Benzeneacetaldehyde, 4-Methyl-.alpha.-oxo-
• CAS NO: 1075-47-4
• Molecular Formula: C₉H₈O₂
• Molecular Weight: 166.17
• Mol File: 1075-47-4.mol
• Article Data: 13

Chemical Properties

• Melting Point: 104-161 °C
• Boiling Point: 323.2°C at 760 mmHg
• Flash Point: 149.3°C
• Appearance: /
• Density: 1.101±0.06 g/cm3(Predicted)
• Vapor Pressure: 0.000109mmHg at 25°C
• CAS DataBase Reference: 4-METHYLPHENYLGLYOXAL HYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLPHENYLGLYOXAL HYDRATE(1075-47-4)
• EPA Substance Registry System: 4-METHYLPHENYLGLYOXAL HYDRATE(1075-47-4)

Safety Data

• Hazardous Substances Data: 1075-47-4(Hazardous Substances Data)

Usage

General Description

4-METHYLPHENYLGLYOXAL HYDRATE is a chemical compound with the molecular formula C10H10O3. It is a hygroscopic white to yellow solid, and it is commonly used as a chemical intermediate in the synthesis of pharmaceuticals, dyes, and polymers. 4-METHYLPHENYLGLYOXAL HYDRATE is known for its ability to undergo several chemical reactions, including condensation, oxidation, and reduction. It is also used in the production of high-performance polymers and resins. Additionally, 4-METHYLPHENYLGLYOXAL HYDRATE is known for its potential as an antimicrobial agent and for its use in organic synthesis.

InChI:InChI=1/C9H8O2.H2O/c1-7-2-4-8(5-3-7)9(11)6-10;/h2-6H,1H3;1H2

Upstream product

• 79-36-7 dichloroacethyl chloride 
• 108-88-3 toluene 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 40805-62-7 2-iodo-1-(4-methylphenyl)ethanone 
• 1855-08-9 1-(p-Tolyl)-1,2-propanedione 
• 4079-54-3 2-hydroxy-1-p-tolyl-ethanone 
• 619-41-0 4-(bromoacetyl)toluene 
• 139016-20-9 (S)-1-(4-methylphenyl)-1,2-ethanediol 
• 4209-24-9 p-methylphenacyl chloride 
• 4974-59-8 2,2-dichloro-4'-methylacetophenone 
• 16208-14-3 2,2-dihydroxy-1-(p-tolyl)ethanone 

Downstream Products

• 861366-07-6 p-tolyl-glyoxylohydroximic acid 
• 18584-20-8 (R)-para-methylmandelic acid 
• 17565-28-5 p-tolyl-glyoxal-bis-phenylhydrazone 
• 2431-23-4 4-methylbenzoin 
• 123488-72-2 2-Hydroxy-2-(pyridin-2-ylamino)-1-p-tolyl-ethanone 
• 122479-53-2 3-hydroxy-6-methoxy-2-(4'-tolyl)imidazo<1,2-b>pyridazine 
• 125794-30-1 6-benzylthio-3-hydroxy-2-(4'-methylphenyl)imidazo<1,2-b>pyridazine 
• 152945-43-2 Cyano-acetic acid 1-cyclohexylcarbamoyl-2-oxo-2-p-tolyl-ethyl ester 
• 101128-43-2 isopropyl-2-oxo-2-(4-tolyl)acetate 
• 130159-25-0 isopropyl hydroxy(4-methylphenyl)acetate 
• 33063-19-3 3-phenyl-6-(p-tolyl)-1,2,4-triazine 
• 2172-22-7 1-Methyl-4-(α-hydroxy-α-acetamino-acetyl)-benzol 
• 24407-35-0 2-(Dimethyl-hydrazono)-1-p-tolyl-ethanone 
• 141861-49-6 1-(cyclohexylcarbamoyl)-2-oxo-2-p-tolylethyl acetate 

Relevant articles and documents

Copper-Catalyzed Enantioselective Hetero-Diels-Alder Reaction of Danishefsky's Diene with Glyoxals

(Chemical Equation Presented) The highly enantioselective hetero-Diels-Alder reaction of Danishefsky's diene with glyoxals was developed by virtue of a readily accessible chiral copper catalyst. This efficient transformation provided a facile and scalable

A 2 - cyano - 4 - chloro - 5 - (4 - methyl phenyl) imidazole synthesis method

The invention relates to a synthetic method for 2-cyano-4-chloro-5-(4-methylphenyl)imidazole. The synthetic method comprises the following steps: (1) by taking p-methylacetophenone as a raw material, carrying out a halogenating reaction under a light condition to obtain a compound I; (2) dissolving the obtained compound I in a solvent, stirring the mixture to react at a certain temperature, and performing cooling and suction-filtering to obtain a compound II; (3) dissolving the obtained compound II in a solvent and carrying out a reaction with glyoxal and hydroxylamine sulphate at a certain temperature to obtain a compound III; and (4) dissolving the obtained compound III in a solvent, carrying out a reaction with sulfoxide chloride in an ice bath in a manner of raising the temperature to room temperature and keeping the temperature for the reaction, dropwise adding sulfur chloride, and after reaction, washing the product to obtain a compound IV which is 2-cyano-4-chloro-5-(4-methylphenyl)imidazole. The synthetic method is good in atom economy, simple and convenient in process operation and high in product yield and industrial application value.

Iodine-mediated oxidative annulation for one-pot synthesis of pyrazines and quinoxalines using a multipathway coupled domino strategy

An efficient iodine-mediated oxidative annulation of aryl acetylenes-arylethenes-aromatic ketones with 1,2-diamines for the synthesis of pyrazines and regioselective synthesis of quinoxalines is presented. A multipathway coupled domino approach has been developed for the one-pot synthesis of 1,4-diazines with high functional group compatibility.