1758-98-1

Usage

Uses

Used in Pharmaceutical Synthesis:
4,6-Dihydroxy-2-methoxypyrimidine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of bioactive compounds. Its unique structure allows for the creation of diverse medicinal agents.
Used in Agrochemical Synthesis:
In the agrochemical industry, 4,6-Dihydroxy-2-methoxypyrimidine is utilized as a building block for the development of agrochemicals, potentially enhancing crop protection and yield through its incorporation into various chemical formulations.
Used in Antioxidant Applications:
4,6-Dihydroxy-2-methoxypyrimidine is used as an antioxidant agent due to its capacity to neutralize free radicals, thereby protecting cells from oxidative stress and potential damage.
Used in Antitumor Applications:
4,6-DIHYDROXY-2-METHOXYPYRIMIDINE is explored for its antitumor properties, making it a candidate for use in cancer research and therapeutic development. Its potential to interfere with tumor growth and progression is of significant interest in oncology.
Used in Disease Treatment Research:
4,6-Dihydroxy-2-methoxypyrimidine is used in research for the treatment of various diseases, given its demonstrated biological activities, as a potential therapeutic agent to address unmet medical needs.

InChI:InChI=1/C5H6N2O3/c1-10-5-6-3(8)2-4(9)7-5/h2H,1H3,(H2,6,7,8,9)

Upstream product

• 5329-33-9 o-methylisourea hydrochloride 
• 108-59-8 malonic acid dimethyl ester 
• 859822-65-4 O-methyl isourea hydrogen sulfate 
• 105-53-3 diethyl malonate 

Downstream Products

• 1074-40-4 4,6-dichloro-2-methoxypyrimidine 
• 1334406-37-9 4-{2-methoxy-6-[2-(4-trifluoromethoxyphenyl)ethylamino]pyrimidin-4-yl}morpholine-2-carboxylic acid 
• 1334406-55-1 ((R)-1-{2-methoxy-6-[2-(4-trifluoromethoxyphenyl)ethylamino]pyrimidin-4-yl}pyrrolidin-3-yl)acetic acid 
• 1334406-71-1 [(R)-1-(6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)pyrrolidin-3-yl]acetic acid 
• 1334406-66-4 [1-(6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)piperidin-2-yl]acetic acid ethyl ester 
• 1334406-64-2 1-(6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)piperidine-2-carboxylic acid ethyl ester 
• 1334406-62-0 [4-(6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)piperazin-1-yl]acetic acid ethyl ester 
• 1334406-61-9 4-{2-methoxy-6-[2-(4-trifluoromethoxyphenyl)ethylamino]pyrimidin-4-yl}morpholine-2-carboxylic acid ethyl ester 
• 1334406-60-8 trifluoromethanesulfonic acid 6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl ester 
• 1334406-59-5 trifluoromethanesulfonic acid 2-methoxy-6-[2-(4-trifluoromethoxyphenyl)ethylamino]pyrimidin-4-yl ester 

Relevant academic research and scientific papers

Novel Compounds

The present invention relates to the new compounds of general formula I wherein A, U, V, X, Y, R1, R2 and R3 are defined as stated hereinafter, the tautomers, the isomers thereof, the diastereomers, the enantiomers, the hydrates, the mixtures and the salts thereof as well as the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, their use and processes for preparing them.

ANTIPROLIFERATIVE PYRIMIDYL, FUSED PYRIMIDYL AND PYRIMIDYL HYDRAZONES

The present invention is related to a novel series of pyrimidyl or fused pyrimidyl hydrazones. Compounds of Formula (I) wherein A is selected from the group consisting of Formulas (A1), (A2), (A3), (A4), (A5) are useful for the treatment and/or prevention of a proliferative disease.

Pyrimidine derivatives

The present invention relates to novel 5-(ω-substituted amino-alkanoyl amino)pyrimidine derivatives, processes for producing the derivatives, and pharmaceutical compositions containing said derivatives. The compounds in the present invention have potent effects of inhibiting ACAT activity and lowering serum cholesterol. The compounds of the present invention are extremely useful for the treatment and/or prevention of arteriosclerosis or hyperlipidemia.

Piperazinyl derivatives of purines and isosteres thereof as hypoglycemic agents

There are disclosed certain 6-piperazinopurines and heteroaromatic derivatives thereof which have oral hypoglycemic acitivity and with such ability to lower blood sugar are useful in the treatment of type II diabetes and/or obesity with associated insulin