17583-92-5Relevant academic research and scientific papers
Base-mediated synthesis of unsymmetrical 1,3,5-triazin-2-amines via three-component reaction of imidates, guanidines, and amides or aldehydes
Pan, Liyang,Li, Zhenxing,Ding, Tao,Fang, Xiaomin,Zhang, Wenkai,Xu, Hao,Xu, Yuanqing
, p. 10043 - 10050 (2017)
A simple and efficient method for the basemediated synthesis of unsymmetrical 1,3,5-triazin-2-amines has been developed. The protocol uses readily available imidates, guanidines, and amides or aldehydes as the starting materials, cesium carbonate as the base, no catalyst or additive is required, and the three-component reaction provides diverse 1,3,5-triazin-2-amines in moderate to good yields with tolerance of wide functional groups.
