175913-27-6

Basic information

• Product Name: 1H-Indole, 4-Methoxy-7-nitro-
• Synonyms: 1H-Indole, 4-Methoxy-7-nitro-;4-Methoxy-7-nitro-1H-indole
• CAS NO: 175913-27-6
• Molecular Formula: C9H8N2O3
• Molecular Weight: 192.17142
• Mol File: 175913-27-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Indole, 4-Methoxy-7-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 4-Methoxy-7-nitro-(175913-27-6)
• EPA Substance Registry System: 1H-Indole, 4-Methoxy-7-nitro-(175913-27-6)

Safety Data

• Hazardous Substances Data: 175913-27-6(Hazardous Substances Data)

Usage

General Description

1H-Indole, 4-methoxy-7-nitro- is a chemical compound belonging to the indole family. It is a derivative of indole with a methoxy group at the 4-position and a nitro group at the 7-position. 1H-Indole, 4-methoxy-7-nitro- has potential applications in pharmaceuticals and agrochemicals due to its unique chemical properties. It is often used as a building block in the synthesis of various organic compounds and has shown biological activity in some research studies. However, more extensive research is needed to fully understand the potential uses and properties of this compound.

Upstream product

• 860024-83-5 1-(4-fluoroindolin-1-yl)ethanone 
• 552866-98-5 2,3-dihydro-4-fluoro-1H-indole 
• 124-41-4 sodium methylate 
• 1167056-95-2 4-fluoro-7-nitro-1H-indole 
• 387-43-9 4-fluoroindole 
• 146564-00-3 1‐(benzenesulfonyl)‐4‐methoxy‐1H‐indole 

Relevant articles and documents

Synthesis method of 4-fluoro-7-nitroindole or derivatives of 4-fluoro-7-nitroindole

The invention is applicable to the technical field of chemical synthesis, and provides a synthesis method of 4-fluoro-7-nitroindole or derivatives thereof, which comprises the following steps: reacting 4-fluoroindole or derivatives thereof, glacial acetic acid and sodium cyanoborohydride to obtain 4-fluoroindoline or derivatives thereof, reacting the 4-fluoroindoline or derivatives thereof, glacial acetic acid and acetic anhydride to obtain N-acetyl-4-fluoroindoline or a derivative thereof, carrying out nitration reaction on N-acetyl-4-fluoroindoline or a derivative thereof to obtain N-acetyl4-fluoro-7-nitroindoline or a derivative thereof, reacting N-acetyl-4-fluorine 7-nitroindoline or derivatives thereof, sodium hydroxide and 1, 4-dioxane to obtain 4-fluoro-7-nitroindoline or derivatives thereof, and reacting 4-fluoro-7-nitroindoline or derivatives thereof, trichloromethane and manganese dioxide to obtain 4-fluoro-7-nitroindoline or derivatives thereof. The synthesis method provided by the invention is mild in reaction condition and easy to operate.