176097-41-9

Upstream product

• 156793-45-2 3'-O-tert-Butyldiphenylsilyl-5'-iodo-5'-deoxythymidine 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 50-89-5 thymidine 
• 25953-14-4 1-((2R,4S,5S)-4-hydroxy-5-(iodomethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 

Downstream Products

• 206982-57-2 N⁶-benzoyl-5'-O-[(tert-butyl)diphenylsilyl]-2'-deoxy-3'-de(phosphinicooxy)adenylylmethylenesulfonylmethylene-(3'->5')-3'-O-[(tert-butyl)diphenylsilyl]-2',5'-dideoxythymidine 
• 206982-59-4 N⁶-benzoyl-2'-deoxy-3'-de(phosphinicooxy)-5'-O-(4,4'-dimethoxytrityl)adenylylmethylenesulfonylmethylene-(3'->5')-2',5'-dideoxythymidine 
• 206982-58-3 N⁶-benzoyl-2'-deoxy-3'-de(phosphinicooxy)adenylylmethylenesulfonylmethylene-(3'->5')-2',5'-dideoxythymidine 
• 176097-40-8 1-[(2R,4S,5R)-4-(tert-Butyl-diphenyl-silanyloxy)-5-(2-iodo-ethyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Four step synthesis of a 5′-deoxy-5′-iodomethylthymidine

The conversion of an alkylsulfonate to an iodide with triphenylphosphine/iodine in benzene has been performed for a nucleoside. Starting from thymidine, 3′-protected 5′-deoxy-5′-iodomethylthymidine was synthesized in 4 steps.