17612-91-8

Usage

Uses

Used in Pharmaceutical Industry:
THIOACETIC ACID S-(2-AMINO-ETHYL) ESTERHYDROCHLORIDE is used as a synthetic reagent for the preparation of psammaplin A analogs, which are potent histone deacetylase inhibitors. These analogs have potential applications in the development of novel therapeutics for various diseases, including cancer, due to their ability to modulate gene expression and cellular processes.

InChI:InChI=1/C4H9NOS.ClH/c1-4(6)7-3-2-5;/h2-3,5H2,1H3;1H

Upstream product

• 75-36-5 acetyl chloride 
• 60-23-1 Cysteamine 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 114326-10-2 N-(tert-butoxycarbonyl)-2-(acetylthio)ethylamine 

Downstream Products

• 104071-89-8 S-<(benzyloxycarbonyl)glycyl>-N-acetylcystamine 
• 89052-99-3 N-(2-acetylthioethyl)-3-(benzyloxycarbonylamino)propionamide 
• 97314-02-8 Thioacetic acid S-[2-(4-benzyloxycarbonylamino-butyrylamino)-ethyl] ester 
• 120627-05-6 carbobenzoxy-valinyl-N-(S-acetyl)-cysteamine 
• 97313-99-0 N-<(benzyloxycarbonyl)glycyl>-S-acetylcysteamine 
• 143799-93-3 N-<(tert-butyloxycarbonyl)phenylalanyl>-S-acetyl-cysteamine 
• 3651-67-0 N-methylmorpholine hydrochloride 
• 311343-00-7 N-(N-acetyl-S-trityl-L-cysteinyl)-S-acetylcysteamine 
• 1427774-93-3 (E)-(S)-2-(3-(3-bromo-4-methoxyphenyl)-2-(hydroxyimino)propanamido)ethyl ethanethioate 
• 1427774-95-5 (S)-2-(3-(3-bromo-4-methoxyphenyl)-2-oxopropanamido)ethyl ethanethioate 
• 97314-00-6 N-(Z-L-ALANYL)-S-ACETYLCYSTEAMINE 

Relevant academic research and scientific papers

PRODUCTION PROCESSES OF S- AND O-DIACYLATED GAMMA-GLUTAMYL-CYSTEAMINE PRODRUGS

Methods are provided for the synthesis of a compound of formula (X). R2 is selected from -H, -C1-C4-alkyl,-C2-C4-alkenyl and C1-C4-aryl; R3 is selected from -C(O)H and

PANTETHEINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGIC DISORDERS

Compounds having the following formula (I): Formula I and pharmaceutically acceptable salts thereof, wherein A, B, D, E and R1 are as defined herein, are provided. Methods comprising the use of such compounds for the treatment of neurological disorders, such as pantothenate kinase-associated neurodegeneration, and pharmaceutical compositions containing such compounds, and their use in the treatment of neurological disorders, also are provided.

Synthesis of conjugated diacetylene, metal-chelating monomers for polymerizable monolayer assemblies.

[see structure]. Self-assembled monolayers (SAMs) of thiols on gold have been used for numerous applications. For protein targeting applications, one successful strategy is to use a metal-chelating SAM. It has also been demonstrated that polymerized SAMs

SYNTHESE DANS LA SERIE DES PHENANTHRIDINES. IV. PREPARATION DE NOUVEAUX RADIOPROTECTEURS A MOTIF PHENANTHRIDINE

New phenanthridines substituted in the 6-position by a β-aminoethylthiol chain have been synthesized.These new products are easily obtained from 6-methylphenanthridine by a Mannich reaction or from 6-bromophenanthridine by substitution.From the 6-carboxaldehydophenanthridine and the β-aminoethylthiol, the corresponding thiazolidine or imine are obtained.These compounds are likely to be new radioprotectors.