3651-67-0

Basic information

• Product Name: N-METHYLMORPHOLINE HYDROCHLORIDE
• Synonyms: N-METHYLMORPHOLINE HYDROCHLORIDE;N-METHYLMORPHOLINEHCl,99+%;N-METHYLMORPHOLINEHYDROCHLORIDE,99+%;4-methylmorpholine,hydrochloride;4-Methylmorpholine hydrochloride (1:1)
• CAS NO: 3651-67-0
• Molecular Formula: C₅H₁₂NO*Cl
• Molecular Weight: 137.61
• EINECS: 222-893-8
• Mol File: 3651-67-0.mol
• Article Data: 21

Chemical Properties

• Melting Point: 203-211 °C
• Boiling Point: 114.1°Cat760mmHg
• Flash Point: 23.9°C
• Appearance: /
• Density: 0.931g/cm³
• Storage Temp.: Flammables area
• CAS DataBase Reference: N-METHYLMORPHOLINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYLMORPHOLINE HYDROCHLORIDE(3651-67-0)
• EPA Substance Registry System: N-METHYLMORPHOLINE HYDROCHLORIDE(3651-67-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-22
• Hazardous Substances Data: 3651-67-0(Hazardous Substances Data)

Usage

Chemical Properties

white to pale yellow hygroscopic powder

InChI:InChI=1/C5H11NO.ClH/c1-6-2-4-7-5-3-6;/h2-5H2,1H3;1H

Upstream product

• 17612-91-8 1-[(2-aminoethyl)sulfanyl]ethan-1-one hydrochloride 
• 27486-87-9 N-acetyl-S-trityl-L-cysteine 
• 4345-03-3 vitamin E succinate 
• 109-02-4 4-methyl-morpholine 
• 3140-73-6 2-chloro-4,6-dimethoxy-1 ,3,5-triazine 
• 158722-22-6 (4S,5R)-2,4-diphenyl-4,5-dihydrooxazole-5-carboxylic acid 
• 98-79-3 L-Pyroglutamic acid 
• 3398-70-7 (2R,4'R,8'R)-α-tocopheramine 
• 32159-21-0 Cbz-L-pGlu-OH 
• 110-91-8 morpholine 
• 50-00-0 formaldehyd 
• 186581-53-3 diazomethane 
• 36851-80-6 nitrosomethylurea 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 

Downstream Products

• 109-01-3 1-methyl-piperazine 
• 15648-16-5 4-methylmorpholine - borane (1/1) 
• 3074-43-9 1-methyl-4-phenylpiperazine 

Relevant articles and documents

Reductive Alkylation of Amines with Carboxylic Ortho Esters

We have demonstrated for the first time that carboxylic ortho esters could be used as an alkylating agent in the reductive alkylation of amines. A variety of amines, including amino acid esters, were alkylated affording mono-alkylated products with high selectivity in practical to high yields using standard heterogeneous catalysts. By applying acyclic ortho esters alkylation was completed at room temperature. (Figure presented.).

Optimized triazine-mediated amidation for efficient and controlled functionalization of hyaluronic acid

Triazine-based coupling agents have the potential to replace carbodiimides in the functionalization of hyaluronic acid (HA) giving derivatives with high degrees of substitution (DS) under mild conditions with excellent efficiency. Kinetics of the triazine

Vitamin E conjugates

Vitamin E conjugates, methods for their preparation, and compositions that include the conjugates. The vitamin E conjugates include a tocopherol moiety covalently coupled through a linker moiety to either a pyroglutamate moiety, a pyrrolidinone moiety, or a gentisic acid moiety.