176220-08-9Relevant academic research and scientific papers
A concise synthesis of 7-Desmethylasteriscanolide and the discovery of an unusual fragmentation reaction to the related asteriscunolide skeleton
Booker-Milburn, Kevin I.,Cowell, Justin K.,Harris, Laurence J.
, p. 12319 - 12338 (1997)
A concise synthesis of 7-desmethylasteriscanolide is described. The key features include an efficient intramolecular [2+2] photocycloaddition of the α,β-unsaturated acid-ether 29 followed by a Curtius rearrangement/ruthenium tetroxide/fragmentation sequen
An intramolecular [2+2] photocycloaddition-fragmentation approach towards the total synthesis of asteriscanolide
Booker-Milburn, Kevin I.,Cowell, Justin K.
, p. 2177 - 2180 (1996)
A new route towards the Asteriscanolide skeleton is described. The key features include an efficient intramolecular [2+2] photocycloaddition of the α,β-unsaturated acid-ether 10 followed by a Curtius rearrangement/ ruthenium tetroxide/ fragmentation sequence to yield the cyclooctane lactones 13 and 14.
