Tetrahedron Letters p. 2177 - 2180 (1996)
Update date:2022-08-31
Topics:
Booker-Milburn, Kevin I.
Cowell, Justin K.
A new route towards the Asteriscanolide skeleton is described. The key features include an efficient intramolecular [2+2] photocycloaddition of the α,β-unsaturated acid-ether 10 followed by a Curtius rearrangement/ ruthenium tetroxide/ fragmentation sequence to yield the cyclooctane lactones 13 and 14.
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(1996)