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176251-49-3

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176251-49-3 Usage

General Description

8,8-difluoro-1,4-dioxaspiro[4.5]decane is a specialized chemical compound belonging to the class of organofluorines. This unique subclass of organic compounds is characterized by the presence of a carbon-fluorine bond. The name of this chemical compound refers to its specific molecular structure, which includes a spiro formation. This means the molecule contains two cyclical structures, specifically a 4-atom ring and a 5-atom ring, that meet at one specific atom. The exact properties, use, and toxicology of this specific compound may depend on various factors and it does not appear to be widely studied or utilized in commercial applications as of present.

Check Digit Verification of cas no

The CAS Registry Mumber 176251-49-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,2,5 and 1 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 176251-49:
(8*1)+(7*7)+(6*6)+(5*2)+(4*5)+(3*1)+(2*4)+(1*9)=143
143 % 10 = 3
So 176251-49-3 is a valid CAS Registry Number.

176251-49-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 8,8-Difluoro-1,4-dioxaspiro[4.5]decane

1.2 Other means of identification

Product number -
Other names 4,4-difluorocyclohexanone ethylene acetal

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:176251-49-3 SDS

176251-49-3Relevant articles and documents

BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF

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Paragraph 00394, (2020/07/07)

Provided is a novel class of orally and/or topically available, selective and potent JAK inhibitors as safe and effective therapeutics against various diseases and disorders. More particularly, provided are pharmaceutical composition of these compounds and methods of their preparation and use thereof.

Method for synthesizing 4-fluorocyclohexanone

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Paragraph 0100-0105, (2018/05/16)

The invention discloses a method for synthesizing 4-fluorocyclohexanone. The method comprises steps as follows: under the alkaline condition, 1,4-cyclohexanedione monoethylene ketal and a fluorinatingagent are subjected to highly selective reaction, and 8-fluoro-1,4-dioxaspiro[4.5]deca-7-ene is produced; 8-fluoro-1,4-dioxaspiro[4.5]decane is prepared from 8-fluoro-1,4-dioxaspiro[4.5]deca-7-ene and hydrogen under the action of a palladium-carbon catalyst; 8-fluoro-1,4-dioxaspiro[4.5]decane is subjected to deprotection with added acid, and 4-fluorocyclohexanone is obtained. According to the method, 1,4-cyclohexanedione monoethylene ketal which is widely sourced and low in cost is taken as a reaction raw material, a high-purity intermediate can be obtained maximumly in each reaction, so thatthe total yield of the whole reaction is high, purity of a final product is up to 98%, the economic benefit is quite remarkable, less environmental pollution is produced, and the method is particularly suitable for large-scale industrial application and popularization.

NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF

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Paragraph 0122-0124, (2014/10/16)

Disclosed are a novel benzamide derivative and pharmaceutical use thereof, and more particularly, a novel benzamide derivative having a structure of Formula 1 or pharmaceutically acceptable salts thereof, and a composition for prevention or treatment of pain or itching including the above material. The novel benzamide derivative and pharmaceutically acceptable salt thereof according to the present invention exhibit excellent pain-suppressive effect and, in particular, pain-suppressive effect in not only a neuropathic animal model but also other models such as a formalin model, and therefore, may be used in suppression of different pains such as nociceptive pain, chronic pain, etc. Further, since it was demonstrated that the present invention displays anti-pruritic efficacy even in an itching model, to which a mechanism and treatment concept established with respect to pain is applied, the present invention may also be effectively used in radical treatment of atopic dermatitis by applying the inventive product to an anti-pruritic composition in order to suppress an initial itching stage and treat symptoms thereof, thus preventing skin damage or inflammation after the scratching stage.

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