176299-73-3Relevant academic research and scientific papers
Synthesis and evaluation of a series of 2'-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(β-L-ribofuranosyl)-1H- benzimidazole (1263W94)
Chan, Joseph H.,Chamberlain, Stanley D.,Biron, Karen K.,Davis, Michelle G.,Harvey, Robert J.,Selleseth, Dean W.,Dornsife, Ronna E.,Dark, Ernest H.,Frick, Lloyd W.,Townsend, Leroy B.,Drach, John C.,Koszalka, George W.
, p. 101 - 123 (2000)
A series of 2'-deoxy analogues of the antiviral agent 5,6-dichloro-2- isopropylamino-1-(β-L-ribofuranosyl)-1H-benzimidazole (1263W94) were synthesized and evaluated for activity against human cytomegalovirus (HCMV) and for cytotoxicity. The 2-substituents
Antiviral benzimidazole nucleoside analogues and method for their preparation
-
, (2008/06/13)
The present invention relates to benzimidazole derivatives and their use in medical therapy particularly for the treatment or prophylaxis of virus infections such as those caused by herpes viruses. The invention also relates to the preparation of the benzimidazole derivatives and pharmaceutical formulations containing them.
