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2-Amino-3,4,5,6-tetrafluorobenzoic acid, also known as 2-amino-3,4,5,6-tetrafluorobenzoate, is a fluorinated derivative of benzoic acid with the molecular formula C7H3F4NO2. It features a benzene ring with four fluorine atoms and an amino group, making it a valuable building block or intermediate in pharmaceutical and chemical synthesis. This white to light yellow crystalline powder is sparingly soluble in water but soluble in organic solvents, and its unique properties and structure contribute to the development of new drugs and agrochemicals.

1765-42-0

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1765-42-0 Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-3,4,5,6-tetrafluorobenzoic acid is used as a building block for the synthesis of new drugs, leveraging its unique structure and properties to enhance drug development and discovery.
Used in Chemical Synthesis:
It serves as an intermediate in chemical synthesis processes, where its fluorinated benzene ring and amino group can be further modified to create a variety of chemical compounds.
Used in Agrochemical Industry:
2-Amino-3,4,5,6-tetrafluorobenzoic acid is utilized as a precursor in the development of agrochemicals, potentially leading to the creation of new pesticides or other agricultural chemicals that can improve crop protection and yield.

Check Digit Verification of cas no

The CAS Registry Mumber 1765-42-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,6 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1765-42:
(6*1)+(5*7)+(4*6)+(3*5)+(2*4)+(1*2)=90
90 % 10 = 0
So 1765-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H3F4NO2/c8-2-1(7(13)14)6(12)5(11)4(10)3(2)9/h12H2,(H,13,14)

1765-42-0 Well-known Company Product Price

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  • Aldrich

  • (381705)  2-Amino-3,4,5,6-tetrafluorobenzoicacid  98%

  • 1765-42-0

  • 381705-1G

  • 1,428.57CNY

  • Detail

1765-42-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Amino-3,4,5,6-tetrafluorobenzoic acid

1.2 Other means of identification

Product number -
Other names 2-AMINO-3,4,5,6-TETRAFLUOROBENZOIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1765-42-0 SDS

1765-42-0Relevant academic research and scientific papers

3,4,5,6-Tetrafluoro-1,2-dehydrobenzene in reactions with 1,2,4-triazines

Kopchuk, Dmitry S.,Chepchugov, Nikolay V.,Gorbunov, Eugeny B.,Zyryanov, Grigory V.,Kovalev, Igor S.,Nosova, Emiliya V.,Slepukhin, Pavel A.,Rusinov, Vladimir L.,Chupakhin, Oleg N.

, p. 1507 - 1512 (2017)

Tetrafluoro-substituted aryne, 3,4,5,6-tetrafluoro-1,2-dehydrobenzene, has been generated in situ from 2-amino-3,4,5,6-tetrafluorobenzoic acid, and its reactivity in reactions with 1,2,4-triazines as dienes has been studied. In these reactions, the corresponding azine ring transformation products, i.e., 1,2,3,4-tetrafluoro-10-(1H-1,2,3-triazol-1-yl)pyrido[1,2-a]indoles, have been obtained, in the case of triazines activated by the presence of electron-withdrawing groups, such as 6-aryl-3-(2-pyridyl)-5-cyano-1,2,4-triazines. The crystal structure of the obtained products was confirmed by X-ray diffraction analysis.

Novel functionalized indigo derivatives for organic electronics

Klimovich, Irina V.,Zhilenkov, Alexander V.,Кuznetsova, Lidiya I.,Frolova, Lubov A.,Yamilova, Olga R.,Troyanov, Sergey I.,Lyssenko, Konstantin A.,Troshin, Pavel A.

, (2020/11/24)

A series of nine novel indigo derivatives, including diiodoindigo, octahalogenated indigoids and compounds with extended π-conjugated system, were synthesized, characterized and investigated as semiconductor materials in organic field-effect transistors (OFETs). Among them, 6,6′-diiodoindigo demonstrated the ambipolar behavior with balanced p-type and n-type mobilities. The complete substitution of hydrogens at the indigo core with halogen atoms led to low electron mobilities in OFETs. An extension of the conjugated system through the introduction of small aromatic substituents (thiophene and phenyl) resulted in predominant p-type behavior. Fusion of aromatic rings resulted in z-shaped dibenzoindigo, which showed poor charge transport properties due to the non-optimal arrangement of molecules along each other in the crystal lattice. The acquired data fulfilled the previously reported model based on the relationship between the chemical nature of substituents and their positions at the indigo core, optoelectronic properties of materials and their performance in OFETs. The results of this study will be useful for rational design of a new generation of the indigo-based semiconductors for biocompatible organic electronics.

Organic electroluminescent materials and devices

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Paragraph 0366-0367, (2021/01/12)

The present invention relates to organic electroluminescent materials and devices. Provided are organometallic compounds. Also provided are formulations comprising these organometallic compounds. Further provided are OLEDs and related consumer products that utilize these organometallic compounds.

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

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Paragraph 0182, (2021/01/26)

Provided are organometallic compounds. Also provided are formulations comprising these organometallic compounds. Further provided are OLEDs and related consumer products that utilize these organometallic compounds.

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