17667-57-1Relevant academic research and scientific papers
12. Approaches to the Synthesis of Cytochalasans. Part 2. Pyrrolinone Derivatives as Basic Units
Schmidlin, Tibur,Tamm, Christoph
, p. 121 - 131 (2007/10/02)
Several attempts to prepare 3-acetyl-5-benzyl-3-pyrrolin-2-one (7) from phenylalanine are described.This goal was only reached formally, because compound 7 exists in the tautomeric form of (Z)-5-benzyl-3-(1'-hydroxyethylidene)-4-pyrrolin-2-one (17) according to the spectral data.The problem of tautomerism in pyrrolinone systems is discussed.
